An interventional study of Pathway to Healthy Aging care in Ageing Well, sponsored by The University of Hong Kong. Active, not recruiting at 1 site in Hong Kong. Open to participants aged 60 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-06-16.
Sponsored by The University of Hong Kong · Not applicable, Interventional, and Supportive care
The goal of this clinical trial is to provide a scientific evaluation on the effects of a protocol-driven Pathway to Healthy Aging (Path-HA) Program on promoting the health-related quality of life and functional abilities of older adults who are at risk of accelerated aging in the community. Participants will be randomized to one of the two study arms: 1) the intervention group to receive a 14-week Path-HA care intervention; and 2) the control group with no Path-HA care intervention.
This assessor-blind, randomized controlled trial evaluates the effects of the Pathway to Healthy Aging Program, which is based on the WHO ICOPE model, on the promotion of the health-related quality of life (primary outcome) as well as functional abilities (secondary outcomes) as defined by the WHO-ICOPE among community-dwelling older adults with accelerated aging. Six health domains including locomotor function, vitality, psychological function, cognitive function, social functions, and overall health-related quality of life are measured. A total of 1000 participants will be recruited. Outcome evaluation takes place at baseline, upon the completion of the care program, and at 6 months thereafter to allow the detection of long-term program benefits. In-depth individual interviews will be conducted to solicit the participants' experience and perceived benefits of the program.
The University of Hong Kong is the lead sponsor of 1,262 studies on the registry; 340 are open to participants now.
Of its 8 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
A 14-week care initiative comprising two phases is provided, which are the 2-week ICOPE-based personalized care planning phase, and the 12-week healthy aging empowerment phase.
Behavioral: Pathway to Healthy Aging care
No care intervention will be provided.
The ICOPE-based personalized care planning comprises two home visits. In 1st visit, a comprehensive assessment proposed by the WHO-ICOPE model is conducted to identify eight possible health problems including malnutrition, reduced physical fitness, fall risk, cognitive decline, insomnia, pain, psychological distress and social loneliness. After health problem identification, each participant receives a personalized care prescription. 2nd visit adopts a goal-oriented empowerment 3-step cycle to personalize the care planning: 1) communicating assessment results to increase healthy self-awareness; 2) supporting setting person-directed goals to address health problems; 3) identifying health actions and personalizing goal setting to participants' contexts. The 12-week healthy aging empowerment comprises three core activities for healthy aging promotion, including interactive health education, health message broadcasts, and three case conferences for goal monitoring and health counseling.
Health-related quality of life
Measured by the EQ-5D-5L questionnaire (scores range from -0.59 to 1.0), with a higher score indicating better quality of life.
Time frame: Changes from baseline to 3-month and 9-month post-intervention
Hand grip strength
Measured by hand-held dynamometer in unit of KG. A larger count indicates a greater grip strength.
Time frame: Changes from baseline to 3-month and 9-month post-intervention
Balancing function
Measured by the Timed Up and Go Test in unit of second. A shorter completion time indicates better mobility and balance.
Time frame: Changes from baseline to 3-month and 9-month post-intervention
Physical mobility level
Measured by the Short Physical Performance Battery (scores range from 0 to 12), with higher scores indicating better physical performance and better mobility functioning.
Time frame: Changes from baseline to 3-month and 9-month post-intervention
Sarcopenia risk
Measured by Sarcopenia and calf circumference scale (SARC-CalF scale). The score ranges from 0 to 20 points, with a score ≥ 11 points suggestive of sarcopenia.
Time frame: Changes from baseline to 3-month and 9-month post-intervention
Nutritional status
Measured by the Mini Nutritional Assessment (scores range from 0 to 30), with a lower score indicating a higher risk of malnutrition.
Time frame: Changes from baseline to 3-month and 9-month post-intervention
Sleep quality
Measured by Insomnia Severity Index questionnaire (scores range from 0 to 28), with higher scores indicating greater severity of insomnia.
Time frame: Changes from baseline to 3-month and 9-month post-intervention
Depressed mood
Measured by the 15-item Geriatric Depression Scale (scores range from 0 to 15), with a higher score indicating a higher risk of depression.
Time frame: Changes from baseline to 3-month and 9-month post-intervention
Cognitive functions
Measured by the 5-minute Montreal Cognitive Assessment Test (scores range from 0 to 30). A raw score of \< 25 in well-educated persons (education \> 12 years) or a raw score of \< 23 in less-educated persons (education ≤ 12 years) is defined as impaired cognition.
Time frame: Changes from baseline to 3-month and 9-month post-intervention
Subjective memory
Measured by Memory Inventory for the Chinese (scores range from 0 to 108), with higher scores indicating more severe subjective memory loss.
Time frame: Changes from baseline to 3-month and 9-month post-intervention
Loneliness
Measured by The 3-Item UCLA Loneliness Scale (scores range from 3 to 9), with higher scores suggesting a higher level of loneliness.
Time frame: Changes from baseline to 3-month and 9-month post-intervention
Social connectedness
Measured by The 8-item version of Social Connectedness Scale (scores range from 8 to 48), with a higher score indicating a greater sense of social connectedness.
Time frame: Changes from baseline to 3-month and 9-month post-intervention
This study is active, not recruiting, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.
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The University of Hong Kong