An interventional study of recto-intercostal fascial plane block and bupivacaine in Recto-intercostal Fascial Plane Block, Epigastric Hernia and Analgesia, sponsored by Tanta University. Completed at 1 site in Egypt. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-07-14.
Sponsored by Tanta University · Not applicable, Interventional, and Treatment
The aim of this study is to evaluate the efficacy and safety bilateral recto-intercostal fascial plane block (RIFPB) in epigastric hernia.
Epigastric hernias are usually occult in obese patients, and their symptoms may mimic peptic ulcer or gallbladder disease . Hernia repair is associated with considerable postoperative pain.
The recto-intercostal fascial plane block (RIFPB) is a new novel approach that was developed by Tulgar et al., 2023 who hypothesized that when we inject a local anesthetic into the interfacial plane just inferolateral to the xiphoid, between the rectus abdominis muscle and the 6-7th costal cartilages (hence, between the cartilages and the intercostal muscles between them), blockade of the anterior branches of the nerves passing through this area can be guaranteed.
1,190 studies on the registry are indexed under Agnosia; 507 are open to participants now.
This study's enrollment of 40 is below the median of 77 across 1,023 interventional studies indexed under Agnosia.
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Exclusion Criteria:
Patients will receive bilateral Recto-Intercostal Fascial Plane Block (RIFPB) using 20 mL of bupivacaine 0.25% on each side.
Procedure: recto-intercostal fascial plane block · Drug: bupivacaine
Patients will not receive the block.
Patients will receive bilateral recto-intercostal fascial plane block using 20 mL of bupivacaine 0.25% on each side.
bupivacaine 0.25%
Time to the 1st rescue analgesia
Rescue analgesia in the form of 3 mg of IV morphine will be given if the numeric rating scale (NRS) score \> 3. NRS (0 represents "no pain" while 10 represents "the worst pain imaginable").
Time frame: 24 hours postoperatively
Total morphine consumption in the 1st 24hr
Rescue analgesia in the form of 3 mg of IV morphine will be given if the numeric rating scale (NRS) score\> 3.
Time frame: 24 hours postoperatively
Pain score
Each patient will be instructed about postoperative pain assessment with the Numeric Rating Scale (NRS) score. NRS (0 represents "no pain" while 10 represents "the worst pain imaginable"). Postoperative pain using NRS at rest and during coughing or movement will be measured at PACU, 2h. 4hr, 6h, 8h, 12h, 18h and 24h postoperative
Time frame: 24 hours postoperatively
Intraoperative fentanyl consumption
Additional bolus doses of fentanyl 1 µg/kg IV will be given if there is increase in heart rate or mean arterial blood pressure more than 20% of the base line (after exclusion of other causes than pain).
Time frame: Intraoperatively.
Intraoperative mean arterial pressure
Mean arterial pressure (MAP) will be recorded preoperative, before performing of block, and every 15 min till the end of surgery.
Time frame: Till the end of surgery.
Intraoperative heart rate
Heart rate (HR) will be recorded preoperative, before performing of block, and every 15 min till the end of surgery.
Time frame: Till the end of surgery.
Complications
Such as pneumothorax, nausea, vomiting, hematoma, hypotension, bradycardia and local anesthetic toxicity will be recorded.
Time frame: 24 hours postoperatively
Plan to share: Yes — The data will be available upon a reasonable request from the corresponding author after the end of study for one year.
Supporting information: Study protocol
No publications or documents are linked to this record.
This study is completed, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.
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Tanta University