ClinicalTrials.gg
RecruitingNCT06083324EXERT-CUpdated Jul 8, 2026

EXErcise Regimen Designed to Improve Functional Mobility, Body Composition, and Strength After Treatment for Cancer

An observational study in Cancer, sponsored by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute). Recruiting at 1 site in United States. Open to participants aged 20 Years to 89 Years. Per ClinicalTrials.gov, last updated 2026-07-08.

Sponsored by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) · Observational

From the registry’s dates

  • Started Feb 2023; still recruiting 3 years 9 months later.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
100
Ages
20 Years to 89 Years
Sex
All
01

Study summary

This protocol seeks to analyze patient outcomes of the standard of care, monitored group exercise regimen of high-load resistance training and functional exercises with compound movements under close supervision on individuals who have been treated for cancer.

02

Conditions studied

  • Cancer

Keywords

  • exercise
  • resistance training
03

In context

Neoplasms

10,818 studies on the registry are indexed under Neoplasms; 2,324 are open to participants now.

This study's planned enrollment of 100 is below the median of 200 across 2,638 observational studies indexed under Neoplasms.

Browse Neoplasms studies →

Lead sponsor

Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) is the lead sponsor of 49 studies on the registry; 20 are open to participants now.

Of its 9 completed or terminated interventional studies of FDA-regulated products, 4 (44%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 89 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Individuals diagnosed with cancer on an exercise program at the AHN Exercise Oncology and Resiliency Center

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  1. Age 20-89 years
  2. Women of must verbally confirm lack of pregnancy prior to enrollment. They should also consent to use adequate during the course of the study.
  3. Participants must be determined capable of engaging in resistance training by exercise personnel and/or study PI
  4. Participants must complete an assessment by EOC staff and be determined safe to engage in the workout regimen by the study exercise personnel.
  5. Individuals not deemed safe to participate in the standard EOC exercise program will be referred to physical therapy or elsewhere

Exclusion criteria

Exclusion Criteria:

1. Severe arthritic, joint, cardiovascular, or musculoskeletal condition that would interfere with exercise program

Terms in these criteria, in plain language(2)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Childbearing potential

Able to become pregnant: from the first period until menopause, unless permanently unable to through surgery (removal of the womb, or of both ovaries or both fallopian tubes).

Criteria for people of childbearing potential usually ask for a negative pregnancy test and for contraception during the study and for a time after it.

Contraception

Ways of preventing pregnancy. “Highly effective” methods fail less than 1% of the time a year when used correctly — for example an IUD or an implant.

Criteria usually say which methods count and how long to keep using them after the last dose, sometimes for male participants too. Some studies accept a partner’s vasectomy if it was confirmed successful and that person is the participant’s only sexual partner.

05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
100 participants (estimated)
Target follow-up
3 Months
Patient registry
Yes

Groups and cohorts

  • General cancer patients

    All patients undergoing treatment for cancer on an exercise regimen

    Other: Dose escalated resistance training

  • Head and neck cancer patients

    All patients undergoing treatment for head and neck cancer on an exercise regime

    Other: Dose escalated resistance training

  • Colorectal cancer patients

    All patients undergoing treatment for colorectal cancer on an exercise regime

    Other: Dose escalated resistance training

  • Pancreatic cancer patients

    All patients undergoing treatment for pancreatic cancer on an exercise regime

    Other: Dose escalated resistance training

  • Metastatic breast cancer patients

    All patients undergoing treatment for metastatic breast cancer on an exercise regime

    Other: Dose escalated resistance training

Interventions

  • OtherDose escalated resistance training

    All individuals will be engaging in resistance training during and/or after their cancer treatment

06

What researchers measure

Primary outcomes

  1. Determine changes in fat mass in pounds from before to after the nutrition and exercise regimen via bioimpedance analysis

    Measurement on bioimpedance analysis machine (Inbody 970)

    Time frame: 3 months

  2. Determine changes in fat mass in pounds from before to after the nutrition and exercise regimen via ultrasound

    Measurement via ultrasound and calculation with Jackson-Pollack calculations

    Time frame: 3 months

  3. Determine changes in muscle mass in pounds from before to after the nutrition and exercise regimen

    Measurement on bioimpedance analysis machine (Inbody 970)

    Time frame: 3 months

Secondary outcomes

  1. Determine changes in overall score of functional movement screen (FMS) from before to after the nutrition and exercise regimen

    Determine changes in overall score of functional movement screen (FMS) from before to after the nutrition and exercise regimen

    Time frame: 3 months

  2. Determine changes in Y-balance score for each leg

    Y-balance score adds up the distance each leg can move in the front and side directions, divided by the length of the hip. This correlates inversely with fall risk.

    Time frame: 3 months

  3. Determine changes in strength via load measured in pounds from before to after the nutrition and exercise regimen

    Load is calculated by multiplying sets by repetitions by weight lifted for a specific exercise

    Time frame: 3 months

  4. Determine changes in EQ-5D responses 1-5 and overall score from before to after the nutrition and exercise regimen

    EQ-5D asks 5 questions rates from 1-5 and an overall rating of health

    Time frame: 3 months

07

Study locations

1 of 1 sites recruiting
  • AHN CI Exercise Oncology and Resiliency Center
    Pittsburgh, Pennsylvania 15202, United States
    Recruiting
    • Colin E Champ, MD, CSCS · Contactcolin.champ@ahn.org · 412-734-7605
    • Chris Peluso, BS · Sub investigator
08

References and documents

Publications

  • Champ CE, Carpenter DJ, Diaz AK, Rosenberg J, Ackerson BG, Hyde PN. Resistance Training for Patients with Cancer: A Conceptual Framework for Maximizing Strength, Power, Functional Mobility, and Body Composition to Optimize Health and Outcomes. Sports Med. 2023 Jan;53(1):75-89. doi: 10.1007/s40279-022-01759-z. Epub 2022 Sep 29. PubMed 36175646 ↗

Individual participant data

Plan to share: Undecided

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Feb 2023 (actual). Primary completion is estimated for Jan 2027, 47 months after the start.

Of 1,098 non-industry observational studies under Neoplasms, half reached primary completion within 61 months of starting (the median), counting those still running; a quarter within 24 and three quarters within 227. This study's planned 47 months is below that.

Counting every sponsor, half of 1,246 studies reached it within 58 months; a quarter within 24 and three quarters within 210.

Neoplasms covers many different conditions, not one, so the studies compared here vary widely. Read these figures as a rough guide.

How these figures are worked out, and which studies are left out of them.

Registered
Oct 9, 2023
First posted
Oct 16, 2023
StartActual
Feb 3, 2023
Primary completionEst.
Jan 16, 2027
CompletionEst.
Jan 16, 2028
Last update
Jul 8, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jul 8, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06083324
Lead sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Responsible party
Colin Champ, MD (Radiation Oncologist, Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)) — Principal investigator
First posted
Oct 16, 2023
Start date
Feb 3, 2023
Primary completion
Jan 16, 2027 (estimated)
Completion
Jan 16, 2028 (estimated)
Last update
Jul 8, 2026

Study contacts

Samantha Campbell
Contact
samantha.campbell@ahn.org
(412) 330-6151

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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