An interventional study of SuCCESs in Sickle Cell Disease, sponsored by University of Maryland, Baltimore. Active, not recruiting at 2 sites in United States. Open to participants aged 6 Years to 17 Years. Per ClinicalTrials.gov, last updated 2026-04-21.
Sponsored by University of Maryland, Baltimore · Not applicable, Interventional, and Treatment
The Sickle Cell Children's Exercise Study (SuCCESs) will explore the feasibility and effects of a moderate intensity strengthening, balance, speed, and agility intervention program in children with sickle cell disease.
Participants will perform the baseline assessment and after six weeks of performing the SuCCESs program the participants will perform a post-intervention assessment. Participants will be asked to attend a total of six physical therapy in-person sessions (1x/week) at the University of Maryland Department of Physical Therapy and Rehabilitation Science and to perform 12 home program sessions.
1,103 studies on the registry are indexed under Anemia, Sickle Cell; 235 are open to participants now.
This study's planned enrollment of 20 is below the median of 40 across 750 interventional studies indexed under Anemia, Sickle Cell.
Browse Anemia, Sickle Cell studies →University of Maryland, Baltimore is the lead sponsor of 687 studies on the registry; 130 are open to participants now.
Of its 90 completed or terminated interventional studies of FDA-regulated products, 63 (70%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
There will be no control group and only one intervention delivered
Behavioral: SuCCESs
strengthening and endurance exercises
knee extension strength
dynamometry to measure knee extension strength
Time frame: week 1 and week 7
Rate of Muscle Activation
Electromyography used to measure rate of muscle activation
Time frame: week 1 and week 7
exercise tolerance
6-Minute Walk Test used to measure exercise tolerance
Time frame: week 1 and week 7
locomotor efficiency
oxygen uptake used to measure locomotor efficiency
Time frame: week 1 and week 7
number of sessions attended
attendance
Time frame: throughout the entire study week 1, weeks 2-6, six weeks of intervention, and week 7
Plan to share: No
This study is active, not recruiting, as verified in Feb 2026. You cannot join it, but the record below documents what was studied.
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University of Maryland, Baltimore