An interventional study of Skin Barrier Oral Supplement in Rosacea and Systemic Inflammation, sponsored by Integrative Skin Science and Research. Recruiting at 1 site in United States. Open to participants aged 30 Years to 70 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-08-27.
Sponsored by Integrative Skin Science and Research · Not applicable, Interventional, and Treatment
The purpose of this study is to evaluate how supplementation will alter the skin and the gut barrier and inflammation in those with rosacea.
Rosacea is a chronic inflammatory condition that widely prevalent in the general population and is associated with both inflammation and dysfunction of the skin barrier. Gut dysfunction has been shown to be present in those with rosacea. This study evaluates how the use of a supplement may improve the gut and skin barrier as well as reduce general inflammation.
233 studies on the registry are indexed under Rosacea; 23 are open to participants now.
This study's planned enrollment of 24 is below the median of 61 across 200 interventional studies indexed under Rosacea.
Browse Rosacea studies →Integrative Skin Science and Research is the lead sponsor of 35 studies on the registry; 12 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Ways of preventing pregnancy. “Highly effective” methods fail less than 1% of the time a year when used correctly — for example an IUD or an implant.
Criteria usually say which methods count and how long to keep using them after the last dose, sometimes for male participants too. Some studies accept a partner’s vasectomy if it was confirmed successful and that person is the participant’s only sexual partner.
Contraception
Ways of preventing pregnancy. “Highly effective” methods fail less than 1% of the time a year when used correctly — for example an IUD or an implant.
Criteria usually say which methods count and how long to keep using them after the last dose, sometimes for male participants too. Some studies accept a partner’s vasectomy if it was confirmed successful and that person is the participant’s only sexual partner.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Dietary Supplement: Skin Barrier Oral Supplement
Supplment powder
Transepidermal water loss (TEWL)
Change in the facial transepidermal water loss (TEWL) using the Vapometer.
Time frame: 8 weeks
Blood hs-CRP level
Change in blood hs-CRP level through blood spot testing
Time frame: 8 weeks
Intestinal permeability
Change in intestinal permeability through a urine based test by Genova Diagnostics
Time frame: 4 weeks
Intestinal permeability
Change in intestinal permeability through a urine based test by Genova Diagnostics
Time frame: 8 weeks
Fecal levels of calprotectin
Change in fecal levels of calprotectin through a stool sample
Time frame: 4 weeks
Fecal levels of calprotectin
Change in fecal levels of calprotectin through a stool sample
Time frame: 8 weeks
Transepidermal water loss (TEWL)
Change in the facial transepidermal water loss (TEWL) using the Vapometer.
Time frame: 4 weeks
Blood hs-CRP level
Change in blood hs-CRP level through blood spot testing
Time frame: 4 weeks
Mood Questionnaire
A survey to assess changes in mood
Time frame: 4 weeks
Mood Questionnaire
A survey to assess changes in mood
Time frame: 8 Weeks
Digestive Questionnaire
A survey to assess digestive health
Time frame: 4 weeks
Digestive Questionnaire
A survey to assess digestive health
Time frame: 8 weeks
Inflammatory lesions on the face
Change in number of inflammatory lesions on the face
Time frame: 4 weeks
Inflammatory lesions on the face
Change in number of inflammatory lesions on the face
Time frame: 8 weeks
Facial erythema
Change in appearance of facial erythema measured by photographic analysis (BTBP 3D Camera System)
Time frame: 4 weeks
Facial erythema
Change in appearance of facial erythema measured by photographic analysis (BTBP 3D Camera System)
Time frame: 8 weeks
Plan to share: No
No publications or documents are linked to this record.
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