An observational study in Atelectasis and Pediatric Anesthesia, sponsored by Vittore Buzzi Children's Hospital. Completed at 1 site in Italy. Open to participants aged 0 Years to 18 Years. Per ClinicalTrials.gov, last updated 2024-04-17.
Sponsored by Vittore Buzzi Children's Hospital · Observational
Children have a highly compliant chest wall and atelectasis formation occurs often during pediatric anesthesia. Inhalation induction is commonly performed in pediatric anesthesia but it is still unclear if this can have an effect on the development of atelectasis. Aim of this study is to investigate the impact of inhalation versus intravenous induction on atelectasis formation during anesthesia induction in children. Atelectasis will be evaluated with lung ultrasound before induction and right after induction.
Respiratory complications, among which atelectasis, are a common cause of adverse events in pediatric anesthesia. Lung ultrasound (LUS) examination is a point of care, non-invasive, radiation-free tool with high sensitivity and specificity for the identification of anesthesia-induced atelectasis in children.
Inhalation induction is commonly performed in pediatric anesthesia to avoid pain at venipuncture or to facilitate vein cannulation. This technique has been associated with a higher rate of respiratory adverse events but no study has investigated the role of inhalation or intravenous induction on lung atelectasis development in pediatric anesthesia.
The investigators will perform this study aiming to describe the impact of inhalation versus intravenous induction technique on atelectasis formation during anesthesia induction in children of different ages.
301 studies on the registry are indexed under Pulmonary Atelectasis; 80 are open to participants now.
This study's enrollment of 326 is above the median of 72 across 73 observational studies indexed under Pulmonary Atelectasis.
Browse Pulmonary Atelectasis studies →Vittore Buzzi Children's Hospital is the lead sponsor of 10 studies on the registry; 5 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Children under 18 years of age scheduled for general anesthesia due to surgery.
Exclusion Criteria:
Patients who will be induced via mask with inhalators anesthetic gases
Other: Type of anesthesia induction
Patients who will be induced with intravenous anesthetics
Other: Type of anesthesia induction
Patients will receive inhalatory or intravenous anesthesia at their choice; both groups will be evaluated with lung ultrasound after induction to detect ultrasonografic signs of atelectasis
Global LUS score
Sum of the LUS scores given to all the lung areas. Score points vary from 0 to 3, where 0 means normality of the lung and 3 refers to complete loss of aeration-tissue-like pattern or consolidation.
Time frame: Upon completion of induction and subsequent controls at end of surgery and 1 postoperative day
Signs of atelectasis
Number of lung areas presenting a sub pleural consolidation
Time frame: Upon completion of induction and and subsequent controls at end of surgery and 1 postoperative day
Plan to share: No
This study is completed, as verified in Apr 2024. You cannot join it, but the record below documents what was studied.
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Vittore Buzzi Children's Hospital