An observational study in Mitral Stenosis, sponsored by Assiut University. Not yet recruiting. Open to participants aged 16 Years to 70 Years. Per ClinicalTrials.gov, last updated 2023-10-05.
Sponsored by Assiut University · Observational
To detect short-term impacts of successful balloon mitral valvuloplasty on right ventricular function
In patients with mitral valve stenosis, right ventricular failure may develop either by the rheumatic process directly or through hemodynamic alterations resulting from pulmonary vascular changes.
Right ventricular (RV) function plays an important role in development of clinical symptoms and prognosis in patients with mitral stenosis (MS).This is primarily affected by hemodynamic effects on RV due to pulmonary hypertension(PH).
In the last two decades, Percutaneous Transluminal Mitral Commissurotomy (PTMC) has become the treatment of choice for patients with symptomatic rheumatic MS . Using this method,Mitral Valve Area (MVA) can be increased, which can improve the hemodynamic and clinical features of patients with MS .
RV functional assessment is difficult and not done routinely because of its complex anatomy and high load dependence.
Different modalitis are used to assess RV function as Tissue Doppler and two-dimensional (2D) speckle tracking method has been used to quantify strain for assessment Myocardial strain is a measure of tissue deformation, which is expressed as a percentage change.
58 studies on the registry are indexed under Mitral Valve Stenosis; 21 are open to participants now.
This study's planned enrollment of 30 is below the median of 301 across 21 observational studies indexed under Mitral Valve Stenosis.
Browse Mitral Valve Stenosis studies →Assiut University is the lead sponsor of 4,901 studies on the registry; 2,098 are open to participants now.
Of its 13 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
Patients with severe mitral stenosis,not impairment left ventricular function
Patient with isolated mitral stenosis (except those with mild mitral regurgitation and are candidate for PTMC by 2D Echo evaluation).
Exclusion Criteria:
To compare RV function before and after PTMC
echocardiogram
Time frame: 1 year
To measure the right side pressure changes invasively before and after PTMC
Right sided heart catheterization
Time frame: 1 year
To compare the effect of PTMC on RV function in patient with AF and sinus rythm
Time frame: 1year
No study locations are listed for this record.
This study is not yet recruiting, as verified in Sep 2023. You cannot join it, but the record below documents what was studied.
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Assiut University