An observational study in Infarction, Brain, Embolism and Atrial Fibrillation, sponsored by Centro Hospitalar De São João, E.P.E.. Completed at 1 site in Portugal. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2023-08-30.
Sponsored by Centro Hospitalar De São João, E.P.E. · Observational
This multicenter international prospective cohort study will include patients with AIS with a known or newly diagnosed anticoagulant-naïve AF. All centers will use the same transcranial Doppler machine for one-hour monitoring with bilateral 2-MHz probes within 24 hours of symptom onset. Recordings will be analyzed for MES by a blinded central reader. The primary aim is to determine the proportion of patients with MES and the association of MES with functional outcomes assessed by a modified Rankin scale (mRS) score at 90 days.
93 studies on the registry are indexed under Brain Infarction; 19 are open to participants now.
This study's enrollment of 61 is below the median of 477 across 23 observational studies indexed under Brain Infarction.
Browse Brain Infarction studies →Centro Hospitalar De São João, E.P.E. is the lead sponsor of 12 studies on the registry; 2 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Acute ischemic stroke admitted to the Stroke Unit, history of AF/flutter, or a new diagnosis of AF at the time of stroke, and able possibility to be monitored within 24 hours after symptom onset.
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Exclusion Criteria:
Other: The presence and rate of MES measured by TCD monitoring
TCD monitoring within 24 hours from the last known well time. Bilateral M1 segments of middle cerebral artery were insonated at a single depth with 2-MHz transducers secured by a probe-holder.
Prevalence of MES
Time frame: Within 24 hours of symptom onset
Poor functional outcome
Time frame: 90-days after stroke
Ordinal Shift Analysis of mRS scale score
Time frame: 90-days after stroke
Ran from Jun 2019 to primary completion in Aug 2022, 38 months.
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This study is completed, as verified in Aug 2023. You cannot join it, but the record below documents what was studied.
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Centro Hospitalar De São João, E.P.E.