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Active, not recruitingNCT06011837Updated May 14, 2026

Effects of Altered Auditory Feedback on Speech Fluency

An interventional study of Altered Auditory Feedback in Stuttering, Adult, sponsored by Massachusetts Institute of Technology. Active, not recruiting at 1 site in United States. Open to participants aged 18 Years to 100 Years. Per ClinicalTrials.gov, last updated 2026-05-14.

Sponsored by Massachusetts Institute of Technology · Not applicable, Interventional, and Supportive care

Phase
Not applicable
Study type
Interventional
Enrollment
100
Allocation
Not applicable
Ages
18 Years to 100 Years
Sex
All
01

Study summary

The purpose of the study is to use altered auditory vocal feedback to increase fluency in people who stutter and to examine changes in this effect over the course of a one month period occurring outside the laboratory setting.

Read the detailed description

The Mumble Melody app applies voice transformations (or "modes") to a user's voice in real-time while they are speaking. The modes include Unaltered, Whisper, Reverberated, and Harmonious voice transformations. The Mumble Melody Longitudinal Study is a month-long online study in which the investigators will be investigating the longer term effects of using the Mumble Melody app for people who stutter. During the course of a month, eligible participants will use the Mumble Melody app daily for however long, on whichever modes, and in whichever settings they wish. Additionally, the investigators will be sending an online platform for participants to conduct weekly at-home testing sessions, in which they will be asked to record their voice during various speech tasks, both with and without the Mumble Melody app. During testing sessions, the investigators will collect voice recordings from participants.

Step 1: Participants will sign a consent form via Redcap. Participants will need an Apple device compatible with the Mumble Melody app.

Step 2: Participants will receive an additional form via Redcap through which they can input information about what device they will be using for the Mumble Melody study, as well as shipping information to receive wired headphones and a headphone jack (which are necessary to use the app).

Step 3: Participants conduct an initial screening session through an online platform, in which they respond to 3 90-second open questions and conduct a passage reading task. The investigators will be collecting voice recordings as they speak within the sessions.

Step 4: Participants' eligibility will be determined using the voice recordings received from step 3. The amount of stuttering-like events and total number of syllables within the recordings will determine if participants have a moderate to severe stutter, meaning they will be eligible for the study.

Step 5: Eligible participants are shipped wired headphones and a headphone jack adapter

Step 6: Participants will fill out an initial survey and optional OASES (Overall Assessment of the Speaker's Experience of Stuttering) assessment of through an online platform.

Step 7: Participants conduct a baseline testing session. During this testing session, participants will answer survey questions, record answers to 2 90-second open response questions without using the Mumble Melody app, follow a step-by-step guide to download and set up the Mumble Melody app, record answers to 2 90-second open response for each of the 4 modes on the Mumble Melody app, and finally record answers to 2 90-second open response questions without using the Mumble Melody app.

Step 8: Step 8: For the following 28 days, participants will be told to use the app as they wish. The investigators will collect app usage logs, which provide timestamps indicating which mode was used and length of use. Participants will receive an additional monetary reward if they use the app for at least 5 minutes for 4 out of 6 days each week.

Step 9: Participants conduct 4 testing sessions, one at the end of each week of the study (day 8, 15, 22, and 29). During each testing session, participants will answer survey questions, record answers to 2 90-second open response questions without using the Mumble Melody app, record answers to 2 90-second open response for each of the 4 modes on the Mumble Melody app, and finally record answers to 2 90-second open response questions without using the Mumble Melody app.

Step 10: After the study, participants will be sent a final survey asking questions on their experience throughout the study and their feedback for the app.

02

Conditions studied

  • Stuttering, Adult

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03

Who can participate

Ages eligible
18 Years to 100 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Identifies as a person who stutters
  • Is US citizen or green card holder currently residing in the US
  • Has one of the following Apple devices:
  • iPhone with iOS 12.0 or later
  • iPad with iPadOS 12.0 or later
  • iPod touch with iOS 12.0 or later
  • Mac with macOS 11.0 or later and an Apple M1 chip or later
  • Has a SEPARATE browser-supporting device with a microphone
  • Is able to conduct the study in English
  • Qualifies based on an initial screening evaluation (Greater than 2.5% Stuttering-Like Dysfluencies per syllable)

Exclusion criteria

Exclusion Criteria:

-

04

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
100 participants (estimated)

Study arms

  • Experimental
    Altered Auditory Feedback

    Participants in this arm will use the Mumble Melody application over the course of 1 month

    Device: Altered Auditory Feedback

Interventions

  • DeviceAltered Auditory Feedback

    Mumble Melody is an application that leverages Altered Auditory Feedback (AAF). During AAF, a person's speech is altered in near-real time. Mumble Melody modulates the user's voice and plays it back to them while they are speaking. Included are Unaltered (raw voice), Whisper (voiceless sound), Reverb (cathedral sound), and Harmonized (robotic sound) voice transformations.

    Also known as: Musically Modulated Auditory Feedback, Mumble Melody

05

What researchers measure

Primary outcomes

  1. Significant change in fluency in one of four modes (Unaltered, Whisper, Reverb, Harmonize) between the baseline testing session and the end of week 4.

    Fluency change From Baseline - Week 4 Measured by Stuttering-Like Dysfluencies within voice recordings from participants

    Time frame: Calculated at the end of the study for time points 1-week, 2-weeks, 3-weeks, and 4-weeks

Secondary outcomes

  1. Frequency of Mode Usage

    Number of times participants use each modes per day throughout the study

    Time frame: Calculated every day for 4 weeks

  2. Duration of Mode Usage

    Length of times participants use different modes per day throughout the study

    Time frame: Calculated every day for 4 weeks

  3. Survey data on experience using the application

    A quality of experience survey for participants. This survey includes multiple questions and ratings as described in detail in the study protocol.

    Time frame: immediately after the intervention

  4. Significant change in fluency in one of four modes (Unaltered, Whisper, Reverb, Harmonize) between the baseline testing session and end of week 1, 2, and 3.

    Fluency change From Baseline - Week 1,2,3 Measured by Stuttering-Like Dysfluencies within voice recordings from participants

    Time frame: Calculated at the end of the study for time points: Baseline, 1-week, 2-weeks, 3-weeks, and 4-weeks

  5. Significant change in fluency in the Baseline (No Auditory Feedback) condition between baseline and end of week 1, 2, 3, and 4.

    Fluency change From Baseline - Week 1,2,3,4 Measured by Stuttering-Like Dysfluencies within voice recordings from participants

    Time frame: Calculated at the end of the study for time points: Baseline, 1-week, 2-weeks, 3-weeks, and 4-weeks

  6. Significant change in fluency in the Final (No Auditory Feedback) condition between baseline and end of week 1, 2, 3, and 4.

    Fluency change From Baseline - Week 1,2,3,4 Measured by Stuttering-Like Dysfluencies within voice recordings from participants

    Time frame: Calculated at the end of the study for time points: Baseline, 1-week, 2-weeks, 3-weeks, and 4-weeks

  7. Significant change in fluency for the Final (No Auditory Feedback) condition in comparison to the baseline (No Auditory Feedback) condition, for each testing session

    Fluency change From Baseline (No Auditory Feedback) - Final (No Auditory Feedback) for each Testing Session Measured by Stuttering-Like Dysfluencies within voice recordings from participants

    Time frame: Calculated at the end of the study for time points: Baseline, 1-week, 2-weeks, 3-weeks, and 4-weeks

  8. Significant change in fluency for each mode in comparison to the baseline (No Auditory Feedback) condition, for each testing session

    Fluency change From Baseline (No Auditory Feedback) - each Mode for each Testing Session Measured by Stuttering-Like Dysfluencies within voice recordings from participants

    Time frame: Calculated at the end of the study for time points: Baseline, 1-week, 2-weeks, 3-weeks, and 4-weeks

  9. Significant change in fluency for each non- control mode (Whisper, Reverb, Harmonize) in comparison to the control mode (Unaltered), for each testing session

    Fluency change From Unaltered Mode - Whisper/Reverb/Harmonize modes for each Testing Session Measured by Stuttering-Like Dysfluencies within voice recordings from participants

    Time frame: Calculated at the end of the study for time points: Baseline, 1-week, 2-weeks, 3-weeks, and 4-weeks

06

Study locations

1 site
  • Massachusetts Institute of Technology
    Cambridge, Massachusetts 02139, United States
07

References and documents

Study documents

  • Study protocol · May 1, 2023
  • Statistical analysis plan · May 1, 2023
  • Informed consent form · May 1, 2023

Documents are hosted by the registry — open the source record to download them.

Individual participant data

Plan to share: Yes — Subjects can choose to consent to having their audio recordings and survey answers shared with the researchers of this study and other qualified researchers.

Supporting information: Study protocol, Sap, Icf, Csr, Analytic code

08

Registry details

Key details

Study ID
NCT06011837
Lead sponsor
Massachusetts Institute of Technology
Responsible party
Sponsor
First posted
Aug 25, 2023
Start date
May 26, 2023
Primary completion
Jun 15, 2024
Completion
Jun 1, 2026 (estimated)
Last update
May 14, 2026

Study contacts

Satrajit Ghosh, PhD
principal investigator · Massachusetts Institute of Technology

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is active, not recruiting, as verified in May 2026. You cannot join it, but the record below documents what was studied.

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