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CompletedNCT05984719NDPHUpdated Feb 18, 2026

New Daily Persistent Headache Survey

An observational study in New Daily Persistent Headache (NDPH) and New Daily Persistent Headache, sponsored by The University of Texas Health Science Center, Houston. Completed at 1 site in United States. Open to participants aged 13 Years and older. Per ClinicalTrials.gov, last updated 2026-02-18.

Sponsored by The University of Texas Health Science Center, Houston · Observational

Study type
Observational
Model
Cohort
Time perspective
Cross-sectional
Enrollment
803
Ages
13 Years and older
Sex
All
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Study summary

Purpose: to explore headache characteristics and treatment effects of patient with new daily persistent headache (NDPH) through an online survey.

Research design: Online survey of patients with new daily persistent headache.

Risks: Risks include a breach of confidentiality as well as fatigue from taking the survey online.

Importance of knowledge that may recently be expected to result: The study aims to discover new information in a very understudied disease. This information could, in future studies, help change the diagnostic criteria or lead to new treatment options.

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Conditions studied

  • New Daily Persistent Headache (NDPH)
  • New Daily Persistent Headache

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Keywords

  • Constant headache
  • Refractory headache disorder
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In context

Headache Disorders

145 studies on the registry are indexed under Headache Disorders; 37 are open to participants now.

This study's enrollment of 803 is above the median of 131 across 46 observational studies indexed under Headache Disorders.

Browse Headache Disorders studies →

Lead sponsor

The University of Texas Health Science Center, Houston is the lead sponsor of 897 studies on the registry; 214 are open to participants now.

Of its 173 completed or terminated interventional studies of FDA-regulated products, 142 (82%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
13 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

The population is participants with a diagnosis of NDPH. The NDPH diagnosis must come from a physician and will be further assessed with disease-specific survey questions.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients with NDPH that have been diagnosed by a health care professional (no documentation is needed, participant must simply state that he or she has been diagnosed)

Exclusion criteria

Exclusion Criteria:

  • Unable to speak English (the survey is only in English)
  • Unable to use a computer to take the online survey
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Study design

Observational model
Cohort
Time perspective
Cross-sectional
Enrollment
803 participants (actual)
Patient registry
No

Groups and cohorts

  • New daily persistent headache (NDPH) group

    Participants with NDPH will be administered an online survey.

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What researchers measure

Primary outcomes

  1. Survey data

    Time frame: At study completion, expected to be in 6-12 months.

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Study locations

1 site
  • UTHealth Houston
    Houston, Texas 77030, United States
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References and documents

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 18, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05984719
Responsible party
Mark J Burish (Associate Professor, The University of Texas Health Science Center, Houston) — Principal investigator
First posted
Aug 9, 2023
Start date
Jun 19, 2023
Primary completion
Jan 31, 2024
Completion
Jan 31, 2024
Last update
Feb 18, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2026. You cannot join it, but the record below documents what was studied.

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Discussion

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