An interventional study of Hypnosis and Virtual reality (VR) in Hematologic Diseases, sponsored by Bnai Zion Medical Center. Completed at 1 site in Israel. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-10-02.
Sponsored by Bnai Zion Medical Center · Not applicable, Interventional, and Supportive care
The goal of this clinical trial is to compare the effects of hypnosis, virtual reality or their combination in patients undergoing a bone marrow procedure.
The main question it aims to answer is whether such interventions may relieve anxiety and other symptoms described by patients undergoing the procedure.
Before the bone marrow procedure and after being explained on the study and signing informed consent, the nurse will measure vital signs and participants will fill-out a 2-minutes' questionnaire and will be assigned to one of 3 groups:
Researchers will compare hypnotic script, virtual reality, their combination or none of them to see if they can affect anxiety and other complaints in patients undergoing a bone marrow procedure.
460 studies on the registry are indexed under Hematologic Diseases; 105 are open to participants now.
This study's enrollment of 67 is above the median of 50 across 274 interventional studies indexed under Hematologic Diseases.
Browse Hematologic Diseases studies →Bnai Zion Medical Center is the lead sponsor of 102 studies on the registry; 13 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Patients will be given earphones to hear a hypnotic script that was recorded by Dr. Zahi Arnon, a psychologist specializing in hypnosis after observing about ten bone marrow (BM) examinations at the hematology institute. The length of the recording is about 7 minutes.
Device: Hypnosis
Patients will be connected to a VR device that will transmit to the patient's choice a 3D screen and soothing noise for about 7 minutes.
Device: Virtual reality (VR)
Patients will be given earphones to hear a hypnotic script that was recorded by Dr. Zahi Arnon, a psychologist specializing in hypnosis after observing about ten BM examinations at the hematology institute. The length of the recording is about 7 minutes.
Patients will be connected to a VR device that will transmit to the patient's choice a 3D screen and soothing noise for about 7 minutes.
Symptoms experienced by patients undergoing bone marrow procedure
Measure Yourself Concerns and Wellbeing (MYCAW) questionnaire: requires participants to nominate one or two concerns and, using a seven-point scale from 0 (worse outcome) to 6 (best outcome), to score these concerns and their general feeling of wellbeing
Time frame: Through study completion, an average of 1 hour
Absorption, dissociation, immersion and time perception
Validated questionnaire on absorption, dissociation, immersion and time perception
Time frame: Through study completion, an average of 1 hour
Sedation
Type and dose of sedation used during procedure
Time frame: Through study completion, an average of 1 hour
Use of analgesics
Type and dose of analgesics
Time frame: Through study completion, an average of 1 hour
Blood pressure
Blood pressure
Time frame: Through study completion, an average of 1 hour
Pulse
Pulse
Time frame: Through study completion, an average of 1 hour
Respiratory rate
Respiratory rate
Time frame: Through study completion, an average of 1 hour
Documents are hosted by the registry — open the source record to download them.
Plan to share: No
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Sep 2025. You cannot join it, but the record below documents what was studied.
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Bnai Zion Medical Center