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RecruitingNCT05981677Updated Apr 11, 2024

Social Feedback and Dysfunctional Risk Taking in NSSI Adolescents

An observational study in Nonsuicidal Self Injury and Risk-Taking, sponsored by University of Electronic Science and Technology of China. Recruiting at 1 site in China. Open to participants aged 15 Years to 18 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-04-11.

Sponsored by University of Electronic Science and Technology of China · Observational

From the registry’s dates

  • Primary completion was expected by Jul 2026, 3 months ago, but the record still lists the study as recruiting.
  • Started Dec 2023; still recruiting 2 years 10 months later.
Study type
Observational
Model
Case-control
Time perspective
Cross-sectional
Enrollment
80
Ages
15 Years to 18 Years
Sex
All
01

Study summary

Nonsuicidal self-injury (NSSI) is defined as direct, intentional physical injury without suicidal intention. Problematic interpersonal relationships and decision-making have been demonstrated to play crucial roles in this maladaptive behavior, especially for adolescents. Accumulating evidence suggests that decision processes and risk-taking are strongly influenced by the affective state of the individual. However, whether these interactions are disrupted in NSSI adolescents has not been systematically examined. In the current study, the investigators modified one of the most widely used paradigms for measuring an individual's risk decision-making, the Balloon Analogue Risk Task (BART). The investigators combine social reward (green balloon), punishment (red balloon), and control feedback (yellow balloon), to investigate whether the NSSI adolescents have dysfunctional risk-taking behavior while facing different social outcomes. The investigators recruit one group of NSSI adolescents (n = 40) and one health control (HC) group (n = 40), to compare their risk-related decisions during the emotional BART. The investigators hypothesize that compared to HC, NSSI adolescents will show altered effects of social reward and punishment on risk-related decision-making, in particular higher risk avoidance in the context of social punishment.

02

Conditions studied

  • Nonsuicidal Self Injury
  • Risk-Taking
03

In context

Self-Injurious Behavior

259 studies on the registry are indexed under Self-Injurious Behavior; 95 are open to participants now.

This study's planned enrollment of 80 is below the median of 242 across 32 observational studies indexed under Self-Injurious Behavior.

Browse Self-Injurious Behavior studies →

Lead sponsor

University of Electronic Science and Technology of China is the lead sponsor of 112 studies on the registry; 37 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
15 Years to 18 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Treatment-seeking NSSI individuals will be recruited from local hospitals and HC from the community.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • 15-18 years
  • right-handed
  • normal or corrected normal visual acuity
  • meet the proposed DSM-5 frequency criteria (e.g., ≥5 days of NSSI behaviors in the past year)

Exclusion criteria

Exclusion Criteria:

  • diagnosis of borderline personality disorder, major depressive disorder, other
  • psychiatric disorders, etc.
  • high suicidal risk
  • recent use of medications that can affect neural activity
  • have received or are receiving Dialectical Behavior Therapy (DBT) other treatment for emotional problems within the past 6 months
  • have a contraindication to MRI scanning (e.g., metal implants, claustrophobia or other conditions that make them inappropriate for MRI scanning)
05

Study design

Observational model
Case-control
Time perspective
Cross-sectional
Enrollment
80 participants (estimated)
Patient registry
No

Groups and cohorts

  • NSSI
  • HC
06

What researchers measure

Primary outcomes

  1. Risky avoidance measured by BART

    Adjusted number of pumps (average number of pumps excluding balloons that exploded) as the index of risk avoidance. Alterations in the patients will be determined by using ANOVA models with the group (NSSI vs. HC) as a between-subject factor and emotional feedback (social reward, social punishment, and control) as a within-subject factor.

    Time frame: About 20 minutes

  2. Decision-making measured by BART

    Earned money (total amount of money earned in the task) as the index of decision-making. Alterations in the patients will be determined by using ANOVA models with the group (NSSI vs. HC) as a between-subject factor and emotional feedback (social reward, social punishment, and control) as a within-subject factor.

    Time frame: About 20 minutes

07

Study locations

1 of 1 sites recruiting
  • Sichuan Provincial Center for Mental Health, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China
    Chengdu, Sichuan, China
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 11, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05981677
Responsible party
Benjamin Becker (Professor, University of Electronic Science and Technology of China) — Principal investigator
First posted
Aug 8, 2023
Start date
Dec 6, 2023
Primary completion
Jul 2026 (estimated)
Completion
Jul 2027 (estimated)
Last update
Apr 11, 2024

Study contacts

Benjamin Becker
Contact
ben_becker@gmx.de
+86.028-61830867

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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