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CompletedNCT05979467Updated Aug 7, 2023

The Relationship Between Serum Endocan and ADMA Levels and Penile Doppler Ultrasonography in Erectile Dysfunction

An observational study in Evaluation of the Relationship Between Serum Biomarkers (Endocan and ADMA) and Penile Doppler Ultrasonography Findings of Patients With Severe Erectile Dysf, sponsored by Ankara Etlik City Hospital. Completed at 1 site in Turkey. Open to male participants aged 50 Years to 70 Years. Per ClinicalTrials.gov, last updated 2023-08-07.

Sponsored by Ankara Etlik City Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
73
Ages
50 Years to 70 Years
Sex
Male
01

Study summary

The gold standard diagnosis in patients admitted to the hospital with the complaint of erectile dysfunction is penile doppler ultrasonography. This procedure is an invasive procedure and can cause various complications. Therefore, in this study, we aimed to support and define the diagnosis of erectile dysfunction with some biomarkers that can be measured in blood samples. At this point, we performed penile doppler ultrasonography, which is the gold standard test, for all patients who applied with the complaint of erectile dysfunction, and compared the results of penile doppler and serum biomarkers in the patients.

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Conditions studied

  • Evaluation of the Relationship Between Serum Biomarkers (Endocan and ADMA) and Penile Doppler Ultrasonography Findings of Patients With Severe Erectile Dysf

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Keywords

  • Erectile dysfunction
  • Endocan
  • ADMA
  • Penile Doppler
03

In context

Erectile Dysfunction

683 studies on the registry are indexed under Erectile Dysfunction; 117 are open to participants now.

This study's enrollment of 73 is below the median of 130 across 115 observational studies indexed under Erectile Dysfunction.

Browse Erectile Dysfunction studies →

Lead sponsor

Ankara Etlik City Hospital is the lead sponsor of 166 studies on the registry; 75 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
50 Years to 70 Years
Sexes eligible
Male
Sampling method
Non-probability sample

Study population

tertiary care clinic

Inclusion criteria

  • Patients with severe erectile dysfunction according to International Index of Erectile Function-15 questionnaire
  • Patients who have not received medical or surgical treatment before
  • Patients without comorbidity and related drug use

Exclusion criteria

Exclusion Criteria:

  • Patients who have had previous pelvic trauma or surgery,
  • Patients who have benefited from using phosphodiesterase-5 enzyme inhibitors,
  • Patients with psychogenic erectile dysfunction and moderate or mild erectile dysfunction according to International Index of Erectile Function-15 questionnaire,
  • Patients who have neurological disease, chronic liver disease and patients with chronic renal failure and those who used drugs that could cause erectile dysfunction
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
73 participants (actual)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. To evaluate the relationship between serum endocan (endothelial cell-specific molecule-1), ADMA (asymmetric dimethylarginine) values and penile Doppler ultrasonography findings in patients with severe Erectile dysfunction.

    Time frame: 10 days from the outpatient clinic admission

07

Study locations

1 site
  • Ankara City Hospital Bilkent
    Ankara, 06800, Turkey
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 7, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05979467
Lead sponsor
Ankara Etlik City Hospital
Responsible party
Cagri Akpinar (M.D., Ankara Etlik City Hospital) — Principal investigator
First posted
Aug 7, 2023
Start date
Apr 17, 2017
Primary completion
Jan 20, 2020
Completion
Jun 12, 2020
Last update
Aug 7, 2023

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2023. You cannot join it, but the record below documents what was studied.

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