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Not yet recruitingNCT05974332Updated Aug 3, 2023

Oncostatin M in Ulcerative Colitis Patients

An interventional study of Oncostatin M in Ulcerative Colitis, sponsored by Beni-Suef University. Not yet recruiting. Per ClinicalTrials.gov, last updated 2023-08-03.

Sponsored by Beni-Suef University · Not applicable, Interventional, and Diagnostic

From the registry’s dates

  • Primary completion was expected by Feb 2024, 2 years 7 months ago, but the record still lists the study as not yet recruiting.
Phase
Not applicable
Study type
Interventional
Enrollment
99
Allocation
Randomized
Sex
All
01

Study summary

Ulcerative colitis (UC) is a refractory disease characterized by symptoms such as diarrhea, bloody stools, and abdominal pain with repeated relapses and remissions.

Read the detailed description

Evaluation of UC activity is important, and endoscopic evaluations of mucosal inflammation can facilitate subsequent prognostication. On the basis of these considerations, achievement of mucosal healing is important in inflammatory bowel disease (IBD), and evaluation of IBD using endoscopy is extremely important. However, endoscopic examinations are associated with problems such as physical burden to the patient, cost, and risk of complications.

Thus, to avoid the need for frequent endoscopy, noninvasive biomarkers that accurately reflect the endoscopic activity of UC have emerged, and fecal calprotectin (FC) and the fecal immunochemical occult blood test (FIT) are being widely used in clinical practice.

02

Conditions studied

  • Ulcerative Colitis
03

In context

Colitis

1,073 studies on the registry are indexed under Colitis; 131 are open to participants now.

This study's planned enrollment of 99 is above the median of 60 across 771 interventional studies indexed under Colitis.

Browse Colitis studies →

Lead sponsor

Beni-Suef University is the lead sponsor of 333 studies on the registry; 116 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • All patients aged >18 years and \<80 years, of both gender who diagnosed to have UC and given the consent for participation in the study

Exclusion criteria

Exclusion Criteria:

  • 1- Any patient with systemic inflammation as Bronchial asthma. 2- History of cancer or tumor. 3- Autoimmune disease such as rheumatoid arthritis and systemic lupus erythematous
05

Study design

Phase
Not applicable
Primary purpose
Diagnostic
Allocation
Randomized
Intervention model
Single group
Masking
Single (Participant)
Enrollment
99 participants (estimated)

Study arms

  • Active comparator
    Ulcerative colitis Patients

    45 Patients with UC. The diagnosis of UC will be based on endoscopic finding and histopathological finding

    Diagnostic Test: Oncostatin M

  • Active comparator
    Control

    45 apparently healthy subjects as controls who were not UC

    Diagnostic Test: Oncostatin M

Interventions

  • Diagnostic testOncostatin M

    Test to diagnosis of Ulcerative colitis

06

What researchers measure

Primary outcomes

  1. Identify if oncostatin M is a good marker

    Diagnosis of Ulcerative colitis and follow up

    Time frame: 6 months

07

Study locations

No study locations are listed for this record.

08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 3, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT05974332
Lead sponsor
Beni-Suef University
Responsible party
mohamed gamal mohamed abdel aleem (Doctor, Beni-Suef University) — Principal investigator
First posted
Aug 3, 2023
Start date
Aug 1, 2023 (estimated)
Primary completion
Feb 28, 2024 (estimated)
Completion
Mar 1, 2024 (estimated)
Last update
Aug 3, 2023

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Jul 2023. You cannot join it, but the record below documents what was studied.

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