An interventional study of Heavy slow resistance training and Eccentric exercise training in Rotator Cuff Tendinopathy, Subacromial Impingement Syndrome and Bicep Tendinitis, sponsored by Mustafa Kemal University. Not yet recruiting at 1 site in Turkey. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2024-06-27.
Sponsored by Mustafa Kemal University · Not applicable, Interventional, and Treatment
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Among 69 studies in Shoulder Impingement Syndrome with a site in Turkey — 12 open to participants now, 14 under way, none of them phase 3. Shoulder Impingement Syndrome · Turkey.
Among the 69 studies in Shoulder Impingement Syndrome with a site in Turkey, this one is the 54th largest by planned enrollment of the 55 interventional ones that give a count, is one of 6 that started in 2026, is one of 54 with no phase, reaches primary completion later than 6 of the 13 other live ones, and was the 34th registered.
320 studies on the registry are indexed under Shoulder Impingement Syndrome; 62 are open to participants now.
Browse Shoulder Impingement Syndrome studies →12 of the 69 studies in Shoulder Impingement Syndrome with a site in Turkey are open now. Recruiting first, the newest first:
Kübra Sarıoğlu · Sites in Turkey
Ages 20–40 · Healthy volunteers
Izmir Katip Celebi University · Sites in Turkey
Ages 30–65 · Healthy volunteers
Fenerbahce University · Sites in Turkey
Ages 25–65
Gazi University · Sites in Turkey
Ages 18–55 · Healthy volunteers
Hacettepe University · Sites in Turkey
Ages 18–50
A study can be open while its sites in Turkey have not opened yet or have stopped. Only those recruiting at a site in Turkey →
Of the 32 Shoulder Impingement Syndrome studies recruiting now, 3 (9%) set no upper age limit and 25 (78%) stop at 75 or younger; 1 takes children under 18; 6 take healthy volunteers.
This study: 18 Years to 65 Years · all sexes · no healthy volunteers.
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69 studies; the count open now beside each. This study's row is marked.
First in 2013; this study’s year is marked. 6 started in 2026.
By drug class, each counting the studies that test any of its medicines:
This study's planned enrollment of 20 is below the median of 54 across 271 interventional studies indexed under Shoulder Impingement Syndrome.
Median enrollment 48 across the 55 interventional studies, 77 across the 14 observational. Of the 52 that completed or were terminated, 0 (0%) have results posted.
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None of the 69 has an industry lead sponsor. The 10 most frequent:
Mustafa Kemal University is the lead sponsor of 77 studies on the registry; 18 are open to participants now.
Mustafa Kemal University has 1 study filed under Shoulder Impingement Syndrome — fewer than ten, so there is no comparison to draw.
3 of the studies in Shoulder Impingement Syndrome with a site in Turkey that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07290660Fenerbahce UniversityGraded Motor Imagery and Task-Oriented Exercise in Shoulder Impingement | 2026-12-30 |
| NCT07053566Hacettepe UniversityLatissimus Dorsi Strengthening Exercises in Rotator Cuff Tendinopathy | 2027-05-22 |
| NCT07891481Pamukkale UniversityEffects of Different Kinesio Taping Methods in Subacromial Impingement Syndrome | 2027-10-26 |
Add all 3 to your calendar (.ics) → With an account.
Among the 69 studies in Shoulder Impingement Syndrome with a site in Turkey, from their registry updates:
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Rotator cuff tendinopathy, also called subbracromial impingement syndrome, is one of the most important causes of anterior shoulder pain. Although exercise training is known as an effective intervention method in the treatment of rotator cuff/subacromial impingement problems, there is no definite consensus on which type of exercise is more effective. The aim of this study is to analyze and compare the effects of the Heavy Slow Resistance (HSR) training and eccentric exercise training on pain, function, supraspinatus tendon structure, muscle strength, range of motion, subjective perception of improvement and treatment satisfaction in individuals with subacromial shoulder pain associated with rotator cuff tendinopathy.
Rotator cuff tendinopathy, also called subbracromial impingement syndrome, is one of the most important causes of anterior shoulder pain. The most frequently affected structure in rotator cuff tendinopathies is the supraspinatus tendon due to its position in the subacromial space. Histological examinations of rotator cuff tendinopathy revealed that the structural changes in supraspinatus tendon injuries are similar to those of the patella and Achilles tendon injuries.
In the treatment of Achilles and patellar tendinopathy, it has been shown that eccentric exercise training has positive effects on pain and function, and supports the improvement in the structural and mechanical properties of the tendon. This success of eccentric training in managing lower extremity tendinopathies has encouraged researchers to conduct more scientific studies to develop evidence-based eccentric training guidelines for the conservative treatment of tendinopathies in the shoulder region. Studies showing that eccentric exercise training has positive effects on pain and function in rotator cuff pathologies have begun to take their place in the literature. In some studies, it has been stated that eccentric exercises are a safe and tolerable approach even in patients with rotator cuff tendinopathy who are candidates for arthroscopic subacromial decompression surgery and reduce the number of patients who are candidates for surgery. Again, in a systematic review-meta-analysis study involving individuals with rotator cuff tendinopathy, it was once again summarized that eccentric training has positive effects on pain and function, but it was stated that more studies are needed on this subject.
The HSR training is the repetitive gradual and slow contraction of the muscle against the heaviest possible load that the person can tolerate. In this training, the focus is more on the concentric and eccentric phases of the movement, and these phases are requested to be completed slowly in 3 seconds. As a result, the concentric/eccentric phase of an exercise repetition is performed with maximum weight in 6 seconds in total. There is scientific evidence in the current literature that slow resistance training has positive effects on symptoms and tendon structure in patella and Achilles tendinopathy. Beyer et al. compared eccentric exercise training and HSR training in Achilles tendinopathy and reported that both trainings had equally positive effects. However, scientific studies investigating the effects of slow resistance training in rotator cuff pathologies are mostly new and few in number. In a recent single-blind randomized controlled feasibility study conducted on 22 individuals with rotator cuff-related subacromial shoulder pain, the effects of slow resistance training in addition to traditional physical therapy program and traditional physical therapy program were compared. Schydlowsky et al. In their study comparing the effects of a supervised and home-based physiotherapy program in subacromial impingement syndrome, they did not directly examine the effects of slow resistance training, but used the slow resistance training procedure for the rotator cuff muscles.
Although exercise training is known as an effective intervention method in the treatment of rotator cuff/subacromial impingement problems, there is no definite consensus on which type of exercise is more effective. However, when previous literature studies from 2022 were examined, a single pilot study was found that examined the effect of specific slow resistance training on symptoms in rotator cuff tendinopathy; No studies could be found comparing specific slow slow resistance training with other exercise interventions. The aim of this thesis, which the investigators planned in the light of this information, is to analyze and compare the effects of heavy slow resistance training and eccentric exercise training on pain, function, supraspinatus tendon structure, muscle strength, range of motion, subjective perception of improvement and treatment satisfaction in individuals with subacromial shoulder pain associated with rotator cuff tendinopathy.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The investigators are planning a 6-week rehabilitation program, 2 days a week. The same physiotherapy and home exercise program will be applied to both groups. The physiotherapy and home exercise program will include patient education, stretching, range of motion and posture exercises. Resistance training will consist of different exercise principles but the same types of exercises. Resistance training: Dumball will be used as exercise equipment. Exercise intensity determined using the Numerical Pain Rating Scale (NPRS). Individual loading will be made according to the amount of weight. The maximum amount of pain producing pain less than 4 on the Numerical Pain Assessment Scale will be determined as exercise intensity. It will include 3 different exercises: 1) Full can. 2) External rotation in side lying. 3) Internal rotation in side lying.
Other: Heavy slow resistance training
The investigators are planning a 6-week rehabilitation program, 2 days a week. The same physiotherapy and home exercise program will be applied to both groups. The physiotherapy and home exercise program will include patient education, stretching, range of motion and posture exercises. Resistance training will consist of different exercise principles but the same types of exercises. Resistance training: Dumball will be used as exercise equipment. Exercise intensity determined using the Numerical Pain Rating Scale (NPRS). Individual loading will be made according to the amount of weight. The maximum amount of pain producing pain less than 4 on the Numerical Pain Assessment Scale will be determined as exercise intensity. It will include 3 different exercises: 1) Full can. 2) External rotation in side lying. 3) Internal rotation in side lying.
Other: Eccentric exercise training
Patients will perform the exercises in the concentric and eccentric phases with the maximum amount of weight tolerated at a rate of 3 seconds/repetition. The number of sets\*repetitions is given below. 2-3 minutes rest between sets will be given. 1st week 3\*15 2-3.week 3\*12 4th-5th week 3\*10 6th week 3\*8
Among the patients in the eccentric exercise group, only the eccentric phase of the exercises in the HSR group, will be asked to actively engage with the affected party. The eccentric contraction rate will be set to 6 seconds. Each exercise will be done 3 sets of 15 repetitions. In the next week, progress will be made in exercise intensity according to tolerance and 500 g will be added to the previous weight. will be continued. If patients cannot tolerate the new weight or there is an increase in pain, the same weight will be continued for another week.
The supraspinatus tendon thickness and elasticity
Affected party the supraspinatus tendon thickness and elasticity value will be evaluated by shear-wave elastography by a specialist radiologist.
Time frame: 6 weeks
Isometric muscle strength
Isometric muscle strength of the external and internal rotators of the shoulder and the supraspinatus muscle will be evaluated by manual muscle testing. For manual muscle testing a digital hand-held dynamometer will be used.
Time frame: 6 weeks
Shoulder range of motion
A digital inclinometer will be used to evaluate the range of motion of the shoulder joint. Reviews shoulder flexion, abduction, internal and external rotation movements will be done. Active movement without pain (painless NEH) will be measured. All measurements will be repeated three times and averaged and recorded in degrees.
Time frame: 6 weeks
The level of pain and disability associated with the shoulder
The Shoulder Pain And Disability Index (SPADI), to assess the level of shoulder-related pain and disability will be used.
Time frame: 6 weeks
Shoulder pain severity
The Numerical Pain Rating Scale will be used to assess the severity of shoulder pain.
Time frame: 6 weeks
Plan to share: No
Start is estimated for Jan 2026; primary completion for Apr 2026, 2 months later.
Of 170 non-industry interventional studies with no phase under Shoulder Impingement Syndrome, half reached primary completion within 11 months of starting (the median), counting those still running; a quarter within 5 and three quarters within 24. This study's planned 2 months is below that.
Counting every sponsor, half of 172 studies reached it within 12 months; a quarter within 5 and three quarters within 24.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in Jun 2024. You cannot join it, but the record below documents what was studied.
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Shoulder Impingement Syndrome →
Mustafa Kemal University