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CompletedNCT05945940Updated Oct 6, 2023

Preoperative Nutritional Status and Postoperative Acute Kidney Injury

An observational study in Postoperative Acute Kidney Injury, sponsored by Rao Sun. Completed at 1 site in China. Open to participants aged 65 Years to 100 Years. Per ClinicalTrials.gov, last updated 2023-10-06.

Sponsored by Rao Sun · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
2,977
Ages
65 Years to 100 Years
Sex
All
01

Study summary

There is a high prevalence of postoperative acute kidney injury (AKI) in patients who undergo intra-abdominal surgery, and it is particularly common in the elderly. Identifying high-risk patients for postoperative AKI early can facilitate the development of preventive and therapeutic management strategies.

The goal of this retrospective study is to investigate the predictive value of preoperative nutritional status, as measured by three scoring systems - the geriatric nutritional risk index (GNRI), prognostic nutritional index (PNI), and controlling nutritional status (CONUT) score - on postoperative AKI in elderly patients undergoing major abdominal surgery.

02

Conditions studied

  • Postoperative Acute Kidney Injury
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In context

Acute Kidney Injury

1,594 studies on the registry are indexed under Acute Kidney Injury; 370 are open to participants now.

This study's enrollment of 2,977 is above the median of 151 across 772 observational studies indexed under Acute Kidney Injury.

Browse Acute Kidney Injury studies →

Lead sponsor

Rao Sun is the lead sponsor of 4 studies on the registry; 1 is open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
65 Years to 100 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Elderly patients (aged ≥ 65 years) who underwent a major abdominal surgery under general anesthesia at Tongji Hospital between July 2018 and December 2021 were included in our study.

Inclusion criteria

  1. aged ≥ 65 years
  2. intra-abdominal procedures including gastric, colorectal, pancreatic, prostate, and urinary bladder surgeries, as well as abdominal exploration.
  3. surgery duration lasting longer than 2 hours.

Exclusion criteria

Exclusion Criteria:

  1. patients with an American Society of Anesthesiologists (ASA) physical status V.
  2. those with concurrent cardiac or renal surgeries.
  3. those with end-stage renal disease (i.e. a glomerular filtration rate of 15 mL/min/1.73 m2 or receiving haemodialysis).
  4. those did not have sufficient data required for nutritional evaluation or AKI evaluation.
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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
2,977 participants (actual)
Patient registry
No

Interventions

  • Otherno intervention

    no intervention

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What researchers measure

Primary outcomes

  1. Postoperative acute kidney injury

    In accordance with the KDIGO creatinine criteria: a serum creatinine increases of 26.5 mmol/L within 48 hours or 1.5 times baseline within 7 days after surgery.

    Time frame: Within 7 days after surgery

07

Study locations

1 site
  • Rao Sun
    Wuhan, China
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 6, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05945940
Lead sponsor
Rao Sun
Responsible party
Rao Sun (Associate chief physician, Tongji Hospital) — Sponsor-investigator
First posted
Jul 14, 2023
Start date
Jul 20, 2023
Primary completion
Jul 30, 2023
Completion
Jul 30, 2023
Last update
Oct 6, 2023

Study contacts

Rao Sun, Dr.
principal investigator · Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2023. You cannot join it, but the record below documents what was studied.

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