An observational study in Genetic Disease and Aneuploidy, sponsored by Istituto Clinico Humanitas. Completed. Open to female participants aged 34 Years to 42 Years. Per ClinicalTrials.gov, last updated 2023-07-10.
Sponsored by Istituto Clinico Humanitas · Observational
This monocentric retrospective observational study aims to evaluate the efficacy of pre-implantation genetic testing for monogenic diseases (PGT-M). The effectiveness will be assessed in terms of live birth rate (LBR), cumulative live birth rate (CLBR) per couple, and abortion rate (AR). Considering how many cycles the participants have undergone to achieve a viable blastocyst. The secondary objective is to evaluate the incidence of aneuploidy in unaffected embryos, in order to understand the need for pre-implantation genetic testing for aneuploidy (PGT-A)in addition to PGT-M.
583 studies on the registry are indexed under Genetic Diseases, Inborn; 157 are open to participants now.
This study's enrollment of 76 is below the median of 151 across 239 observational studies indexed under Genetic Diseases, Inborn.
Browse Genetic Diseases, Inborn studies →Istituto Clinico Humanitas is the lead sponsor of 279 studies on the registry; 70 are open to participants now.
Counted across the registry records on this site, refreshed daily.
All 76 participants that underwent PGTM testing in the Fertility Center starting from the beginning of 2016 all through the end of 2022, will be included in the study.
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Exclusion Criteria:
Live birth rate (LBR)
LBR will be measured as a percentage
Time frame: 7 years of inclusion
Cumulative live birth rate (CLBR) per couple
CLBR per couple will be measured as a percentage
Time frame: 7 years of inclusion
Abortion rate (AR)
AR will be measured as a percentage
Time frame: 7 years of inclusion
Aneuploidy
Aneuploidy embryo rate will be measured as a percentage
Time frame: 7 years of inclusion
No study locations are listed for this record.
PDFs hosted by the registry, ClinicalTrials.gov.
This study is completed, as verified in Jun 2023. You cannot join it, but the record below documents what was studied.
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