ClinicalTrials.gg
RecruitingNCT05895422Updated Jun 9, 2023

Functional Outcome After Minimally Invasive Pyeloplasty for Adult Patients With UPJO

A Phase 3 interventional study of pyeloplasty in Ureteropelvic Junction Obstruction, sponsored by Cairo University. Recruiting at 1 site in Egypt. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2023-06-09.

Sponsored by Cairo University · Phase 3, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Jun 2025, 1 year 5 months ago, but the record still lists the study as recruiting.
  • Started Jun 2023; still recruiting 3 years 5 months later.

Help build ClinicalTrials.gg — short surveys, remote interviews or testing, in your language. Take part →

Phase
Phase 3
Study type
Interventional
Enrollment
17
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

an intervention study on adult patients with uretero-pelvic junction obstruction (UPJO) due to crossing vessels would be managed either through classic dismembered pyeloplasty or vascular hitch.

Read the detailed description

in recent studies, some patients with crossing vessels UPJO could be managed by vascular displacement of these vessels, what is named as vascular hitch or vasculopexy in a way to avoid classic dismembered technique. this newer technique is supposed to provide comparable results to the classic technique but with lesser operative time and shorter hospital stay. in the era of minimally invasive procedures, robotic assisted or laparoscopic vascular hitch could provide many advantages over the classic open technique.

02

Conditions studied

  • Ureteropelvic Junction Obstruction
03

In context

Multicystic renal dysplasia, bilateral

26 studies on the registry are indexed under Multicystic renal dysplasia, bilateral; 9 are open to participants now.

This study's planned enrollment of 17 is below the median of 40 across 20 interventional studies indexed under Multicystic renal dysplasia, bilateral.

Browse Multicystic renal dysplasia, bilateral studies →

Lead sponsor

Cairo University is the lead sponsor of 4,951 studies on the registry; 1,463 are open to participants now.

Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • all patients with UPJO above 18 years
  • UPJO caused by crossing vessels confirmed by CT angiography
  • Symptomatic UPJO

Exclusion criteria

Exclusion Criteria:

  • recurrent UPJO after a previous trial of open repair ,
  • secondary UPJO after open renal surgery.
  • UPJO in non functioning kidney
05

Study design

Phase
Phase 3
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
17 participants (estimated)

Study arms

  • Experimental
    vascular hitch

    displacement of the lower polar crossing vessels causing the UPJO

    Procedure: pyeloplasty

  • Active comparator
    Dismembered pyeloplasty

    classic Anderson-Hynes procedure

    Procedure: pyeloplasty

Interventions

  • Procedurepyeloplasty

    repair of the uPJO

06

What researchers measure

Primary outcomes

  1. comparing the two techniques regarding the success rate

    both techniques are supposed to have similar results

    Time frame: 2 years

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: Undecided — the researchers would determine whether they would share or not during the study

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Started Jun 2023 (actual). Primary completion is estimated for Jun 2025, 24 months after the start.

How these figures are worked out, and which studies are left out of them.

Registered
May 31, 2023
First posted
Jun 8, 2023
StartActual
Jun 1, 2023
Primary completionEst.
Jun 1, 2025
CompletionEst.
Jul 1, 2025
Last update
Jun 9, 2023
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jun 9, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05895422
Lead sponsor
Cairo University
Responsible party
Ahmed Rammah (lecturer of urology- faculty of medicine, Cairo University) — Principal investigator
First posted
Jun 8, 2023
Start date
Jun 1, 2023
Primary completion
Jun 1, 2025 (estimated)
Completion
Jul 1, 2025 (estimated)
Last update
Jun 9, 2023

Study contacts

Ahmed M Rammah, MD
Contact
ahmedrammah2013@gmail.com
2001005622939
Islam N Abdel Aziz, M.sc
Contact
islamnasser54asdasd@gmail.com
2001013132994

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Interested in this study?

Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.

Contact study team

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion