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CompletedNCT05894317VACTANEUpdated Feb 24, 2025

Vascular Access Complications for Therapeutic Apheresis in Nephrology

An observational study in Vascular Access Complication and Apheresis Related Complication, sponsored by Central Hospital, Nancy, France. Completed at 1 site in France. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-02-24.

Sponsored by Central Hospital, Nancy, France · Observational

Study type
Observational
Model
Case-only
Time perspective
Retrospective
Enrollment
60
Ages
18 Years and older
Sex
All
01

Study summary

The aim of this study is to describe vascular access complications which are used for therapeutic apheresis in Nephrology.

Read the detailed description

The aim of this study is to describe vascular access complications which are used for therapeutic apheresis in Nephrology.

Complications may include arterio-veinous fistula or graft (AVF or AVG) thrombosis with or without known stenosis; AVF or AVG or central veinous catheter (CVC) infections and CVC dysfunctions.

The investigators may enroll all patients receveing therapeutic apheresis for nephrologic indications in North East France.

Nephrologics indications include :

  • acute or active antibody mediated rejection (ABMR),
  • Goodpasture disease,
  • ANCA vasculitis,
  • thrombotic microangiopathy (TMA),
  • Focal segmental glomerulosclerosis (FSGS),
  • HLA or ABO desensitization for kidney transplantation.

Data inclusion period is from June 2020 to June 2022.

The aim of the study is to describe the proportion and type of complication in the population of patient receving therapeutic apheresis for nephrologic disease in the North East France. Te investigators will study the risk factors that are associated with this complications.

The second aim of the study is to describe the population of patient receving therapeutic apheresis in our unit and in our region.

02

Conditions studied

  • Vascular Access Complication
  • Apheresis Related Complication

Keywords

  • Apheresis
  • DFPP
  • ANCA associated vasculitis
  • Goodpasture syndrome
  • Arterio veinous fistula
  • Arterio veinous graft
03

In context

Lead sponsor

Central Hospital, Nancy, France is the lead sponsor of 778 studies on the registry; 183 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

patients in nephrology receiveing apheresis treatment by filtration or double filtration with arterioveinous fistula or arterioveinous graft or central veinous catheter

Inclusion criteria

  • patients in nephrology receiveing apheresis treatment by filtration or double filtration

Exclusion criteria

Exclusion Criteria:

  • apheresis treatment for other indications
  • centrifugation apheresis treatment
05

Study design

Observational model
Case-only
Time perspective
Retrospective
Enrollment
60 participants (actual)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Vascular access Complication (catheter or AVF/AVG thrombosis/infection) rate in therapeutic apheresis among nephrological diseases

    Percent of patient with Vascular access Complication

    Time frame: june 2020 june 2022

Secondary outcomes

  1. Description of population enrolled

    Description of population treated by therapeutic apheresis in Northeast France

    Time frame: june 2020 june 2022

  2. Comparison of complications rate with literature datas

    Time frame: june 2020 june 2022

07

Study locations

1 site
  • Central Hospital
    Nancy, 54000, France
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 24, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05894317
Lead sponsor
Central Hospital, Nancy, France
Responsible party
CORBEL Alice (Dr.CORBEL Alice Nephrology, MD, Central Hospital, Nancy, France) — Principal investigator
First posted
Jun 8, 2023
Start date
Jun 1, 2020
Primary completion
Jun 30, 2022
Completion
Feb 14, 2025
Last update
Feb 24, 2025

Study contacts

Luc Frimat, MD PhD
principal investigator · CHRU NANCY DRCI

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2025. You cannot join it, but the record below documents what was studied.

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