An observational study in Corneal Wavefront Aberration and SARS-CoV-2, sponsored by Tianjin Eye Hospital. Completed at 1 site in China. Open to participants aged 18 Years to 32 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-05-31.
Sponsored by Tianjin Eye Hospital · Observational
To explore whether cornea structure, and optical quality are affected by the covid-19 infection.
Participants with healthy corneas admitted to Tianjin Eye Hospital from November 25 to January 20, 2022 were followed up . At the end of the follow-up, the investigators recorded in detail whether the patients had undergone real-time reverse transcriptase polymerase chain reaction (covid-19 RT-PCR tests) testing, testing time and results. The presence of PCR-positive during follow-up is considered to be covid-19 infection; PCR-Negative and no symptoms of infection during the follow-up period are considered not infected; participants with symptoms but no PCR test were excluded from the study.Participants were divided into three groups according to the RT-PCR results and the presence or absence of symptoms of infection during follow-up. pentacam (Pentacam HR, Oculus, Wetzlar, Germany) was performed during follow-up and the results were recorded,and the data was statistically managed and compared.
7,640 studies on the registry are indexed under COVID-19; 488 are open to participants now.
This study's enrollment of 110 is below the median of 261 across 3,136 observational studies indexed under COVID-19.
Browse COVID-19 studies →Tianjin Eye Hospital is the lead sponsor of 49 studies on the registry; 15 are open to participants now.
Counted across the registry records on this site, refreshed daily.
patients admitted to refractive center of Tianjin Eye Hospital
Included Criteria
Exclusion Criteria:
unifected with SARS-CoV-2 during follow-up
uninfected at the first visit, have been infected at the second visit
have been infected at twice visit
The value of cornea aberration
The value of aberration data from pentacam during follow-up were compared, including coma, spherical aberration, defocus, and astigmatism
Time frame: 1 months
The value of cornea backscatter
The value of cornea backscatter from pentacam during follow-up were compared, including anterior layer，central layer and posterior
Time frame: 1 months
The value of cornea thickness
The value of cornea thickness from pentacam during follow-up were compared, includig the thinnest point, apex of the cornea.
Time frame: 1 months
Plan to share: Undecided
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This study is completed, as verified in May 2023. You cannot join it, but the record below documents what was studied.
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Tianjin Eye Hospital