An interventional study of PRF and standard third molar surgical removal in Platelet-rich Fibrin, sponsored by Lam Cu Phong. Completed at 1 site in Vietnam. Open to participants aged 18 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-05-19.
Sponsored by Lam Cu Phong · Not applicable, Interventional, and Supportive care
A Randomized, controlled clinical trial and split-mouth design was performed to assess and compare the effect of platelet-rich fibrin (PRF) on soft tissue healing, periodontal pocket depth and alveolar bone height distal to second molar of the study and control groups after third molar surgical removal.
Sample include of participants who had indication of impacted lower third molars extraction on both sides with symmetrically orientation and same difficult index. All participants had same extraction protocol on both side at Department of Oral surgery, Faculty of Odonto-stomatology, University of Medicine and Pharmacy, Ho Chi Minh City.
Soft tissue healing, periodontal pocket depth and distal bone height were evaluation by an independent investigator.
126 studies on the registry are indexed under Periodontal Pocket; 36 are open to participants now.
This study's enrollment of 26 is below the median of 30 across 109 interventional studies indexed under Periodontal Pocket.
Browse Periodontal Pocket studies →This is the only study on the registry with Lam Cu Phong as lead sponsor.
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Exclusion Criteria:
standard third molar surgery following surgical protocol of Department of Oral Surgery, University of Medicine and Pharmacy
Other: standard third molar surgical removal
PRF was applied in third molar socket after removal following surgical protocol of Department of Oral Surgery, University of Medicine and Pharmacy
Other: PRF
centrifuge patient's blood to collect 1 block of yellowish condensed fibrin, which is platelet-rich fibrin
standard third molar surgery following surgical protocol of Department of Oral Surgery, University of Medicine and Pharmacy
periodontal pocket depth
periodontal pocket depth at distal buccal and distal lingual side of second molar
Time frame: 1rst postoperative month
periodontal pocket depth
periodontal pocket depth at distal buccal and distal lingual side of second molar
Time frame: 3rst postoperative month
periodontal pocket depth
periodontal pocket depth at distal buccal and distal lingual side of second molar
Time frame: 6rst postoperative month
distal bone resorption
resorption of alveolar bone height distal to second molar
Time frame: 3rd postoperative month
distal bone resorption
resorption of alveolar bone height distal to second molar
Time frame: 6th postoperative month
soft tissue healing index
soft tissue healing around third molar socket
Time frame: 3rd postoperative day
soft tissue healing index
soft tissue healing around third molar socket
Time frame: 7th postoperative day
This study is completed, as verified in May 2023. You cannot join it, but the record below documents what was studied.
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