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RecruitingNCT05824403PACTOLUpdated Dec 4, 2023

PAncreatic Disease Cohort of TOuLouse

An observational study in Pancreatic Diseases, sponsored by University Hospital, Toulouse. Recruiting at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2023-12-04.

Sponsored by University Hospital, Toulouse · Observational

From the registry’s dates

  • Started Nov 2023; still recruiting 2 years 10 months later.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
300
Ages
18 Years and older
Sex
All
01

Study summary

This study is a prospective cohort dedicated to pancreatic diseases excluding cancer. The aim is to develop positive or differential diagnostic tools between benign potentially malignant or malignant pancreatic pathologies. During this study the investigators collect data and biological samples to support research project.

Read the detailed description

This collection focuses on pathology of the pancreas requiring specific investigations or management for diagnosis or treatment. Pancreatic pathologies can be classified as malignant, potentially malignant or benign tumors. These can be solid or cystic. There is an inflammatory attack on the pancreas, generating acute pancreatitis in the acute period, if the inflammatory manifestations persist, chronic pancreatitis will develop. Some lesions may be at risk of malignancy during their evolution, it is therefore necessary to improve the performance of monitoring and diagnostic tools in order to adapt the management of patients.

02

Conditions studied

  • Pancreatic Diseases

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Keywords

  • Pancreatic cyst
  • Acute pancreatitis
  • chronic pancreatitis
  • Intra Pancreatic Mucinous Neoplasia
  • diagnosis
03

In context

Pancreatic Diseases

169 studies on the registry are indexed under Pancreatic Diseases; 62 are open to participants now.

This study's planned enrollment of 300 is close to the median of 330 across 81 observational studies indexed under Pancreatic Diseases.

Browse Pancreatic Diseases studies →

Lead sponsor

University Hospital, Toulouse is the lead sponsor of 794 studies on the registry; 214 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Sampling method
Non-probability sample

Study population

Patients with pancreatic disease

Inclusion criteria

  • Patients with inflammatory or cystic exocrine pancreatic pathology
  • Patient able to read and understand the information leaflet
  • Patients who have agreed to participate in the study and have signed the free and informed consent
  • Patients affiliated to a social security system (including AME)

Exclusion criteria

Exclusion Criteria:

  • Patient with pancreatic cancer pathology
  • Patients with active cancer, whatever the origin
  • Pregnant or breastfeeding patients
  • Patients under legal protection, guardianship or trusteeship
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
300 participants (estimated)
Patient registry
No
Biospecimen retention
Samples with dna
06

What researchers measure

Primary outcomes

  1. Diagnostic tools

    To develop positive or differential diagnostic tools between benign potentially malignant or malignant pancreatic pathologies

    Time frame: 3 years after the first inclusion

Secondary outcomes

  1. New targets

    To identify new screening targets

    Time frame: 3 years after the first inclusion

  2. Improvement of management

    To improve the management of cystic lesions or Chronic pancreatitis on the decision of therapeutic management

    Time frame: 3 years after the first inclusion

  3. Microbiota

    Study of the microbiota of pancreatic diseases

    Time frame: 3 years after the first inclusion

  4. Clinical data access

    To make available to the scientific community quality material with associated clinical data also of quality

    Time frame: 3 years after the first inclusion

07

Study locations

1 of 1 sites recruiting
  • Rangueil hospital
    Toulouse, France
    • Barbara BOURNET, MD · Contact · bournet.b@chu-toulouse.fr · 0561323235
    • Adrian CULETTO, MD · Sub investigator
    • Karl BARANGE, MD · Sub investigator
    • Louis BUSCAIL, MD · Sub investigator
    • Fabrice MUSCARI, MD · Sub investigator
    • Charlotte MAULAT, MD · Sub investigator
    • Nicolas CARRERE, MD · Sub investigator
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 4, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05824403
Lead sponsor
University Hospital, Toulouse
Responsible party
Sponsor
First posted
Apr 21, 2023
Start date
Nov 28, 2023
Primary completion
Dec 2027 (estimated)
Completion
Dec 2027 (estimated)
Last update
Dec 4, 2023

Study contacts

Barbara BOURNET, MD
Contact
bournet.b@chu-toulouse.fr
0561323235 ext. +33
Cindy CANIVET
Contact
canivet.c@chu-toulouse.fr
05 61 32 20 48
Barbara BOURNET, MD
principal investigator · University Hospital, Toulouse

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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