ClinicalTrials.gg
RecruitingNCT05714111RadonPamsUpdated Sep 23, 2026

Radiology Registry on Pancreatic Malignancies

An observational study in Pancreatic Cancer, Pancreas Neoplasm and Pancreas Disease, sponsored by IRCCS San Raffaele. Recruiting at 1 site in Italy. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-23.

Sponsored by IRCCS San Raffaele · Observational

From the registry’s dates

  • Started Mar 2022; still recruiting 4 years 8 months later.
Study type
Observational
Model
Cohort
Time perspective
Other
Enrollment
1,300
Ages
18 Years and older
Sex
All
01

Study summary

The purpose of this study is to collect all radiological data which evaluated with clinical data may help assess malignancy and prognosis of pancreatic disease.This registry aims to collect retrospective data from 2014 and prospective data until 2027 with a maximum follow-up of 3 years per patient.

Read the detailed description

Single center, observational (retrospective and prospective) will collect all available parameters to assess the clinical outcome of the patients (progression free survival (PFS), overall survival (OS), local progression free survival LTPFS), response to treatment) with pancreatic neoplasms presenting to San Raffaele. Patient assignment to a given diagnostic and/or therapeutic procedure is not related to random assignment methods but is part of the ordinary therapeutic strategy planned for each patient on an individual basis and after multidisciplinary discussion.

02

Conditions studied

  • Pancreatic Cancer
  • Pancreas Neoplasm
  • Pancreas Disease
  • Pancreas Cyst
03

In context

Pancreatic Neoplasms

3,896 studies on the registry are indexed under Pancreatic Neoplasms; 1,007 are open to participants now.

This study's planned enrollment of 1,300 is above the median of 200 across 740 observational studies indexed under Pancreatic Neoplasms.

Browse Pancreatic Neoplasms studies →

Lead sponsor

IRCCS San Raffaele is the lead sponsor of 453 studies on the registry; 234 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients with pancreatic adenocarcinoma, pancreatic neuroendocrine tumors, rare forms of pancreatic cancer (such as ampullary cancer, adenosquamous carcinomas, squamous cell carcinomas, signet ring cell carcinomas, undifferentiated carcinomas, and undifferentiated carcinomas with giant cells) and cystic neoplasms.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • ≥18 years of age
  • Patients with suspect (planned for investigation) or diagnosed pancreatic cancer at any stage.
  • able and willing to sign

Exclusion criteria

Exclusion Criteria:

  • Patients with non-primary pancreatic disease
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

05

Study design

Observational model
Cohort
Time perspective
Other
Enrollment
1,300 participants (estimated)
Patient registry
No
Biospecimen retention
Samples without dna

Interventions

  • OtherRadiology evaluations and interventions

    Diagnostic and interventional radiology procedures

06

What researchers measure

Primary outcomes

  1. Progression- free survival

    Time from start of observation to disease progression

    Time frame: From date of intervention until the date of first documented progression, up to a maximum of 3 years

  2. Local progression free survival

    Time between (start of) a locoregional treatment and local disease progression

    Time frame: From date of intervention until the date of first documented local progression assessed up to a maximum of 3 years

Secondary outcomes

  1. Overall Survival

    The length of time from either the date of diagnosis or the start of treatment for a disease, in which the patients are still alive

    Time frame: From date of treatment until the date of death from any cause assessed up to 3 years

07

Study locations

1 of 1 sites recruiting
08

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Mar 2022 (actual). Primary completion is estimated for Mar 2027, 60 months after the start.

Of 318 non-industry observational studies under Pancreatic Neoplasms, half reached primary completion within 74 months of starting (the median), counting those still running; a quarter within 34 and three quarters within 182. This study's planned 60 months is below that.

Counting every sponsor, half of 352 studies reached it within 60 months; a quarter within 34 and three quarters within 182.

How these figures are worked out, and which studies are left out of them.

Registered
Jan 25, 2023
First posted
Feb 6, 2023
StartActual
Mar 4, 2022
Primary completionEst.
Mar 30, 2027
CompletionEst.
Mar 30, 2030
Last update
Sep 23, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Sep 23, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT05714111
Lead sponsor
IRCCS San Raffaele
Responsible party
Francesco De Cobelli (Head of Radiology, IRCCS San Raffaele) — Principal investigator
First posted
Feb 6, 2023
Start date
Mar 4, 2022
Primary completion
Mar 30, 2027 (estimated)
Completion
Mar 30, 2030 (estimated)
Last update
Sep 23, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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No contact was published for this record. The registry link below has the sponsor’s details.

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Discussion

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