An interventional study of CDC/NTCA guidelines only and LTBI ASSIST and CDC/NTCA guidelines only in Latent Tuberculosis, sponsored by Johns Hopkins University. Completed at 1 site in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-01-03.
Sponsored by Johns Hopkins University · Not applicable, Interventional, and Health services research
Latent Tuberculosis infection (LTBI) guidelines can be complex. LTBI-ASSIST is a web-based interactive tool to navigate US LTBI clinical practice guidelines in a patient-centered format that may guide clinical decision making around Latent TB care.
The research goal is to determine the difference in reported confidence among trainees that are not experts in LTBI care. The investigators further aim to assess if access to the LTBI-ASSIST tool improves clinical decision making in a series of simulated case scenarios containing guideline-derived, multiple choice items, as well as assess the efficiency in navigating the scenarios - measured by time to complete the survey.
The investigators proposed a randomized study design, in which an electronic survey/questionnaire with 4 case scenarios consisting of 14 multiple choice questions. Participants providing informed consent will be randomized to receiving access to either US Centers for Disease Control (CDC)/National Tuberculosis (TB) Controllers Association (NTCA) Guidelines or the LTBI-ASSIST online tool. Those in the experimental arm will further complete a 10 question System Usability Scale to assess usability of the LTBI-ASSIST tool.
All Johns Hopkins medical trainees and residents will be eligible to participate.
1,417 studies on the registry are indexed under Tuberculosis; 208 are open to participants now.
This study's enrollment of 168 is above the median of 150 across 952 interventional studies indexed under Tuberculosis.
Browse Tuberculosis studies →Johns Hopkins University is the lead sponsor of 1,783 studies on the registry; 313 are open to participants now.
Of its 203 completed or terminated interventional studies of FDA-regulated products, 140 (69%) have results posted.
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Exclusion Criteria:
The control group will have a link to US guidelines only and use it as a resource to answer the case vignettes.
Behavioral: CDC/NTCA guidelines only
The intervention group will have a link to both US guidelines, and the LTBI-ASSIST tool as resources to answer the case vignettes.
Behavioral: LTBI ASSIST and CDC/NTCA guidelines only
The control group will have a link to US guidelines only.
The intervention group will have a link to both US guidelines, and the LTBI-ASSIST tool.
Reported confidence with LTBI management [using a Likert scale questionnaire developed by study team]
The primary outcome will be the change in reported confidence with LTBI management, comparing between the control and intervention group. This outcome will be measured using a Likert Scale questionnaire administered pre- and post-intervention asking trainees to rate their confidence in performing critical LTBI care proficiencies.
Time frame: 3 months
Proportion of appropriate LTBI care selection
The number of multiple choice questions answered correctly in the case scenarios comparing between trainees and/or CDC/NTCA guidelines.
Time frame: 3 months
Time to LTBI care selection
The time required for each group to reach a correct answer.
Time frame: 3 months
This study is completed, as verified in Jan 2024. You cannot join it, but the record below documents what was studied.
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