An interventional study of Smartphone-delivered Automated Messaging and Nicotine patch in Smoking Cessation and HIV, sponsored by H. Lee Moffitt Cancer Center and Research Institute. Recruiting at 3 sites in Cambodia. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-08-13.
Sponsored by H. Lee Moffitt Cancer Center and Research Institute · Not applicable, Interventional, and Prevention
The goal of this research study is to test how well an automated text messaging smoking treatment program helps smokers with HIV quit smoking.
1,581 studies on the registry are indexed under Smoking Cessation; 198 are open to participants now.
This study's planned enrollment of 800 is above the median of 164 across 1,423 interventional studies indexed under Smoking Cessation.
Browse Smoking Cessation studies →H. Lee Moffitt Cancer Center and Research Institute is the lead sponsor of 540 studies on the registry; 75 are open to participants now.
Of its 99 completed or terminated interventional studies of FDA-regulated products, 57 (58%) have results posted.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The human immunodeficiency virus, which weakens the immune system.
Many studies now accept people whose HIV is controlled on treatment, judged by the viral load and the CD4 count. Check the limits this study sets.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
HIV
The human immunodeficiency virus, which weakens the immune system.
Many studies now accept people whose HIV is controlled on treatment, judged by the viral load and the CD4 count. Check the limits this study sets.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants will receive brief advice and education materials to quit smoking along with brief weekly assessments to be completed on a smartphone. They will also receive a 8 week supply of of nicotine replacement therapy in the form of nicotine patches.
Drug: Nicotine patch · Behavioral: Brief Advice to Quit and Smoking Cessation Self Help Materials · Behavioral: Diet Assessment
Participants will receive brief advice and education materials to quit smoking, along with brief weekly assessments and an interactive phone-based treatment program delivered on a smartphone. They will also receive a 8 week supply of of nicotine replacement therapy in the form of nicotine patches.
Behavioral: Smartphone-delivered Automated Messaging · Drug: Nicotine patch · Behavioral: Brief Advice to Quit and Smoking Cessation Self Help Materials
An interactive smartphone based intervention will provide weekly smoking-related assessments and personalized automated messages designed to increase motivation, self-efficacy, use of coping skills, social support and to reduce nicotine withdrawal symptoms and stress for a 26 week period.
Participants will be provided with a 8 week supply of nicotine patches
Participants will receive self-help materials from Khmer Quit Now, a national smoking cessation campaign in Cambodia
Participants will be asked to complete brief weekly smartphone assessments about their diet for a 26-week period
Self Reported 7 Day Abstinence Smoking Status
Participants will self report 7-day abstinence smoking status
Time frame: 12 Month Follow-Up
Smoking Status by Expired Carbon Monoxide
Investigators will use a CO monitor to verify smoking status biochemically
Time frame: 12 Month Follow-up
Self Reported 7 Day Abstinence Smoking Status at 3 Months
Participants will self report 7-day abstinence smoking status
Time frame: At 3 Months
Smoking Status by Expired Carbon Monoxide at 3 Months
Investigators will use a CO monitor to verify smoking status biochemically
Time frame: At 3 Months
Self Reported 7 Day Abstinence Smoking Status at 6 Months
Participants will self report 7-day abstinence smoking status
Time frame: At 6 Months
Smoking Status by Expired Carbon Monoxide at 6 Months
Investigators will use a CO monitor to verify smoking status biochemically
Time frame: At 6 Months
Plan to share: Undecided
Started Jan 2023 (actual). Primary completion is estimated for Aug 2027, 55 months after the start.
Of 546 non-industry interventional studies with no phase under Smoking Cessation, half reached primary completion within 24 months of starting (the median), counting those still running; a quarter within 12 and three quarters within 45. This study's planned 55 months is above that.
Counting every sponsor, half of 563 studies reached it within 24 months; a quarter within 12 and three quarters within 44.
How these figures are worked out, and which studies are left out of them.
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
Contact study teamGet an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
H. Lee Moffitt Cancer Center and Research Institute →