An interventional study of Doppler ultrasound in Septic Thrombophlebitis, sponsored by Centre Hospitalier le Mans. Recruiting at 2 sites in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2023-06-15.
Sponsored by Centre Hospitalier le Mans · Not applicable, Interventional, and Diagnostic
Central venous catheters improve the tolerability and feasibility of patient care in the hospital setting by allowing the administration of hyper-osmotic, vesicant and venotoxic fluids. Despite these advantages, the long-term presence of central venous catheters is associated with thrombotic and infectious risks , including catheter-related bacteremia, which can be complicated by septic thrombophlebitis and endocarditis that can lead to death.
Septic thrombophlebitis is a complication of venous catheter infections, which increases the morbidity. It is defined by the presence of a thrombosis in the vein where the venous catheter is located, associated with a bacteremia. A distinction is made between superficial and deep thrombophlebitis.
The frequency of septic thrombophlebitis of venous catheters is variable and poorly described in the literature.
When the diagnosis of septic thrombophlebitis is made, it is recommended to extend the duration of antibiotic therapy, to remove the infected catheter and to prescribe anticoagulant treatment. However, there is no recommendation on the duration of anticoagulation for septic thrombophlebitis, whether it is deep or superficial.
Investigator proposes a prospective and descriptive interventional study to describe the ultrasound evolution of thrombus in patients with septic thrombophlebitis on central venous catheter and midline.
15 studies on the registry are indexed under Thrombophlebitis; 2 are open to participants now.
This study's planned enrollment of 120 is above the median of 104 across 11 interventional studies indexed under Thrombophlebitis.
Browse Thrombophlebitis studies →Centre Hospitalier le Mans is the lead sponsor of 44 studies on the registry; 18 are open to participants now.
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Doppler ultrasound D8, D15, D30, D45, D60 and D90
Diagnostic Test: Doppler ultrasound
Control venous Doppler ultrasound
Evaluation of duration of ultrasound signs of septic thrombophlebitis on central venous catheter and midline
the duration is measured by time from the day of diagnosis of septic thrombophlebitis to the day of disappearance of signs of thrombophlebitis on Doppler ultrasound
Time frame: Day 90
Plan to share: No
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Centre Hospitalier le Mans