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CompletedNCT05737719prehab-ACLUpdated Jun 25, 2026

Utilization of Rehabilitation Prior to Surgery Among Patients With Anterior-cruciate Ligament Knee Injury

An observational study in Anterior-cruciate Ligament Knee Injury, sponsored by Nantes University Hospital. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-06-25.

Sponsored by Nantes University Hospital · Observational

Study type
Observational
Model
Case-control
Time perspective
Other
Enrollment
864,000
Ages
18 Years and older
Sex
All
01

Study summary

This research aims to assess physiotherapy utilization in the treatment of patients with an anterior-cruciate ligament knee injury, when delivered before their surgery (prehab), and its potential effects on absence from work, and patients global health consumptions (before and after the surgery).

Read the detailed description

Based on the codes generated from French National health database, patients with prehab (+post-surgery rehabilitation) will be compared to patients receiving only post-surgery rehabilitation

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Conditions studied

  • Anterior-cruciate Ligament Knee Injury

Keywords

  • Rehabilitation
  • Surgery
  • Health consumption
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In context

Lead sponsor

Nantes University Hospital is the lead sponsor of 825 studies on the registry; 195 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Preparing the patient for a surgical procedure had been well known in physiotherapy.

Presurgical exercise aiming to improve functional capacity before a surgical procedure leads to more rapid postoperative recovery compared with patients who remain physically inactive through the preoperative period

Inclusion criteria

- First episod of ACL-surgery

Exclusion criteria

Exclusion Criteria:

  • No history or previous ACL-surgery
  • No rehabilitation after surgery
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Study design

Observational model
Case-control
Time perspective
Other
Enrollment
864,000 participants (estimated)
Patient registry
No

Groups and cohorts

  • Prehab

    Patients awaiting a knee surgical procedure, and after the surgery

    Behavioral: Rehabilitation before knee surgery (prehab) · Behavioral: Post-surgery rehabilitation

  • Control

    Patients after the surgery

    Behavioral: Post-surgery rehabilitation

Interventions

  • BehavioralRehabilitation before knee surgery (prehab)

    Physiotherapy strategies for preparing the patient awaiting the surgical procedure

  • BehavioralPost-surgery rehabilitation

    Physiotherapy strategies to manage post-surgery recovery

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What researchers measure

Primary outcomes

  1. Consumption of physiotherapy services

    Total number of sessions, frequency (/week)

    Time frame: - 3 months up to surgery

  2. Consumption of physiotherapy services

    Total number of sessions, frequency (/week)

    Time frame: from surgery up to 18 months later

  3. Absence from work

    Number of days

    Time frame: - 3 months up to surgery

  4. Absence from work

    Number of days

    Time frame: from surgery up to 18 months later

Secondary outcomes

  1. Health consumption 1

    Appointments to MD, nurses (total number)

    Time frame: - 3 months up to surgery

  2. Health consumption 1

    Appointments to MD, nurses (total number)

    Time frame: from surgery up to 18 months later

  3. Health consumption 2

    Drugs and medical imaging (total number)

    Time frame: - 3 months up to surgery

  4. Health consumption 2

    Drugs and medical imaging (total number)

    Time frame: from surgery up to 18 months later

  5. Health consumption 3

    Hospital stay (number, length)

    Time frame: from surgery up to 18 months later

  6. Health consumption 4

    Re-injury (surgery, number)

    Time frame: from surgery up to 18 months later

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Study locations

1 site
  • CHU de Nantes
    Nantes, 44093, France
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References and documents

Publications

  • Le Sant G, Frouin A, Gachet L, Lacourpaille L, Nordez A, Bataille E, Gaultier A, Fournier JP. Effects of preoperative treatment on healthcare utilization and return to work for anterior cruciate ligament injuries: a real-world study using the French healthcare database. Phys Sportsmed. 2025 Apr;53(2):159-168. doi: 10.1080/00913847.2024.2435256. Epub 2024 Dec 1. PubMed 39618085 ↗

Individual participant data

Plan to share: No

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 25, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05737719
Lead sponsor
Nantes University Hospital
Responsible party
Sponsor
First posted
Feb 21, 2023
Start date
Jul 1, 2014
Primary completion
Jul 1, 2018
Completion
Jul 1, 2018
Last update
Jun 25, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.

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