An observational study in the Association Between the Arterial Stiffness, Intraoperative Blood Pressure Changes and Genetic Effect, sponsored by National Taiwan University Hospital. Not yet recruiting. Open to participants aged 20 Years to 90 Years. Per ClinicalTrials.gov, last updated 2023-02-15.
Sponsored by National Taiwan University Hospital · Observational
The intraoperative blood pressure changes have been important for postoperative morbidity and mortality. However, some patients did not occur intraoperative hypotension but some patients would have severe intraoperative hypotension. It may be associated with genome related. In this hypothesis, we aim to elucidate the association between the whole exome genome and intraoperaive blood pressure changes.
We aim to elucidate the association between the whole exome genome and intraoperative blood pressure changes.
We will enroll patients older than 20 years old and undergo elective general anesthesia.
Before anesthesia, we will obtain blood sample for whole exome genome test and give arterial line for intraoperative monitor.
After completing surgery, we will follow the patients' all postoperative major organ function.
We hope this study to be able to give us the more information about the specific genetic effect on the arterial stiffness and intraoperative blood pressure changes.
National Taiwan University Hospital is the lead sponsor of 2,563 studies on the registry; 569 are open to participants now.
Of its 11 completed or terminated interventional studies of FDA-regulated products, 2 (18%) have results posted.
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patients recieving general anesthesia
Exclusion Criteria:
patients undergoing general anesthesia
Other: this study did not involve interventions; it only observational study
this study did not involve interventions. This study is an observational study for elucidating the intraoperative blood pressure changes, artierial stiffness, and whole exome genome
The association between the arterial stiffness and whole exome genome
using pearson correlation to describe the association
Time frame: 15 minutes
No study locations are listed for this record.
Plan to share: No — due to ethical concern
No publications or documents are linked to this record.
This study is not yet recruiting, as verified in Feb 2023. You cannot join it, but the record below documents what was studied.
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National Taiwan University Hospital