An interventional study of Clenbuterol and Placebo in Skeletal Muscle Physiology, sponsored by Morten Hostrup, PhD. Recruiting at 1 site in Denmark. Open to participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-01-20.
Sponsored by Morten Hostrup, PhD · Not applicable, Interventional, and Basic science
The purpose of the project is investigate muscle memory and underlying mechanisms in humans following resistance training and use of the anabolic substance clenbuterol.
Morten Hostrup, PhD is the lead sponsor of 17 studies on the registry; 7 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
A recording of the heart’s electrical activity, taken with stickers on the chest, arms and legs. It takes a few minutes and does not hurt.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
ECG (electrocardiogram)
A recording of the heart’s electrical activity, taken with stickers on the chest, arms and legs. It takes a few minutes and does not hurt.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants are randomized to daily ingestion of clenbuterol for a period of 8 weeks, with or without supervised resistance training.
Drug: Clenbuterol
Participants are randomized to daily ingestion of placebo for a period of 8 weeks, with or without supervised resistance training.
Drug: Placebo
Participants ingest 80 micrograms clenbuterol daily during the initial 8-week period. This period is followed by a washout of 16 weeks with no drug and resistance training. Thereafter, an 8-week period with supervised resistance training is commenced, with no drug.
Participants ingest placebo tablets daily during the initial 8-week period. This period is followed by a washout of 16 weeks with no drug and resistance training. Thereafter, an 8-week period with supervised resistance training is commenced, with no drug.
Fiber cross-sectional area
Immunohistochemistry to determine fiber cross-sectional area
Time frame: The change in fiber cross-sectional is assessed at baseline, 8, 24 and 32 weeks
Myonuclei
Immunohistochemistry to determine number of myonuclei
Time frame: The change in myonuclei is assessed at baseline, 8, 24 and 32 weeks
Skeletal muscle proteome
Pathway enrichment analysis of the muscle proteome using mass-spectrometry based proteomics
Time frame: The change in the muscle proteome is assessed at baseline, 8, 24 and 32 weeks
Lean mass
Lean mass assessed by dual X-ray absorptiometry (DXA)
Time frame: The change in lean mass is assessed at baseline, 8, 24 and 32 weeks
Isometric muscle strength
Maximal voluntary isometric contraction of m. quadriceps
Time frame: The change in maximal voluntary isometric contraction is assessed at baseline, 8, 24 and 32 weeks
Dynamic muscle strength
1-repetition maximum
Time frame: The change in 1-repetition maximum is assessed at baseline, 8, 24 and 32 weeks
Sprint performance
Work performed (W) during a sprint on a bicycle ergometer
Time frame: The change in sprint performance is assessed at baseline, 8, 24 and 32 weeks
Satellite cells
Immunohistochemistry to determine number of satellite cells
Time frame: The change in satellite cells is assessed at baseline, 8, 24 and 32 weeks
Plan to share: Undecided
No publications or documents are linked to this record.
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
Contact study teamGet an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Studies of the drug tested here: Clenbuterol
Morten Hostrup, PhD