CompletedNCT05688150Updated Feb 20, 2024

Prevalence and Associated Factors of Sarcopenia Among Elderly Patients in Osteoporosis Clinic

An observational study in Sarcopenia and Osteoporosis, sponsored by Kowloon Hospital, Hong Kong. Completed at 1 site in Hong Kong. Open to participants aged 60 Years and older. Per ClinicalTrials.gov, last updated 2024-02-20.

Sponsored by Kowloon Hospital, Hong Kong · Observational

Study type: Observational
Model: Cohort
Time perspective: Cross-sectional
Enrollment: 94
Ages: 60 Years and older
Sex: All

Study summary

This was a cross-sectional study. Patients who attended the osteoporosis clinic of Kowloon Hospital from June to December 2022 were recruited.

Grip strength and appendicular skeletal muscle mass index were measured with a Jamar dynamometer and a bioimpedance analyser. Since most patients in our clinic are of Chinese ethnicity, the diagnostic criteria in the Consensus Update on Sarcopenia Diagnosis and Treatment by the Asian Working Group for Sarcopenia in 2019 was utilised. The diagnosis of sarcopenia was established by the presence of both low grip strength (Male: \< 28 kg, Female \< 18 kg) and low appendicular skeletal mass (Male: \< 7.0 kg/m2, Female: \< 5.7 kg/m2)

Conditions studied

Sarcopenia
Osteoporosis

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Keywords

osteosarcopenia
sarcopenia
osteoporosis
geriatric medicine

In context

Osteoporosis

1,640 studies on the registry are indexed under Osteoporosis; 212 are open to participants now.

This study's enrollment of 94 is below the median of 174 across 446 observational studies indexed under Osteoporosis.

Browse Osteoporosis studies →

Lead sponsor

Kowloon Hospital, Hong Kong is the lead sponsor of 9 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

Who can participate

Ages eligible: 60 Years and older
Sexes eligible: All
Accepts healthy volunteers: No
Sampling method: Non-probability sample

Study population

Patients who attended the osteoporosis clinic of Kowloon Hospital from June to December 2022.

Inclusion criteria

Patients aged 60 years old or above
Diagnosed with osteoporosis by: Fragility fracture or T-score ≤-2.5 SDs at any site on DXA scan and;
Able to read and write Chinese

Exclusion criteria

Exclusion Criteria:

Unable to maintain standing posture for bioimpedance analysis
Modified Functional Ambulation Classification (MFAC) ≤ IV
Incompetent in giving consent
Unable to follow instructions
Implanted with metal in any of four limbs
Implanted with pacemaker, implantable cardioverter defibrillator or any other types of electrical device

Study design

Observational model: Cohort
Time perspective: Cross-sectional
Enrollment: 94 participants (actual)
Patient registry: No

What researchers measure

Primary outcomes

Prevalence of Sarcopenia
The diagnosis of sarcopenia would be established by the co-existence of low grip strength and low appendicular skeletal muscle mass.
Time frame: June - December 2022
Grip strength
Grip strength would be measured with Jamar digital dynamometer.
Time frame: June - December 2022
Appendicular Skeletal Muscle Mass Index
Appendicular Skeletal Muscle Mass Index would be measured with bioimpedance analyzer.
Time frame: June - December 2022

Secondary outcomes

Association between BMI and Sarcopenia.
BMI would be measured on clinic attendance.
Time frame: June - December 2022
Association between Frailty and Sarcopenia.
Clinical Frailty Scale would be documented in clinical consultation.
Time frame: June - December 2022
Association between Charlson Comorbidities Index and Sarcopenia
Components of Charlson Comorbidities Index would be extracted from medical record.
Time frame: June - December 2022
Association between Bone Mineral Densities and Sarcopenia
Bone mineral densities of spine and neck of femur would be extracted from the report of dual-energy X-ray absorptiometry.
Time frame: June - December 2022

Study locations

1 site

Kowloon Hospital
Kowloon, Hong Kong

References and documents

Publications

Chen LK, Woo J, Assantachai P, Auyeung TW, Chou MY, Iijima K, Jang HC, Kang L, Kim M, Kim S, Kojima T, Kuzuya M, Lee JSW, Lee SY, Lee WJ, Lee Y, Liang CK, Lim JY, Lim WS, Peng LN, Sugimoto K, Tanaka T, Won CW, Yamada M, Zhang T, Akishita M, Arai H. Asian Working Group for Sarcopenia: 2019 Consensus Update on Sarcopenia Diagnosis and Treatment. J Am Med Dir Assoc. 2020 Mar;21(3):300-307.e2. doi: 10.1016/j.jamda.2019.12.012. Epub 2020 Feb 4. PubMed 32033882 ↗

Individual participant data

Plan to share: No

Updates

Tracking since Sep 25, 2026

No changes since tracking began. The registry record was last updated on Feb 20, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗

Registry details

Key details

Study ID: NCT05688150
Lead sponsor: Kowloon Hospital, Hong Kong
Responsible party: Leung Hin Cheung (Principal Investigator, Kowloon Hospital, Hong Kong) — Principal investigator
First posted: Jan 18, 2023
Start date: Jun 20, 2022
Primary completion: Dec 12, 2022
Completion: Feb 28, 2023
Last update: Feb 20, 2024

Oversight

Data monitoring committee: Yes
FDA-regulated drug: No
FDA-regulated device: No

View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2024. You cannot join it, but the record below documents what was studied.

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