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CompletedNCT05680376Updated Jan 11, 2023

Thyroid Hormone Values and Anti-thyroid Peroxidase Antibody Positivity in Recurrent Pregnancy Loss

An observational study in Autoimmune Thyroiditis and Recurrent Miscarriage, sponsored by Zonguldak Bulent Ecevit University. Completed at 1 site in Turkey. Open to female participants aged 18 Years to 45 Years. Per ClinicalTrials.gov, last updated 2023-01-11.

Sponsored by Zonguldak Bulent Ecevit University · Observational

Study type
Observational
Model
Case-control
Time perspective
Retrospective
Enrollment
103
Ages
18 Years to 45 Years
Sex
Female
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Study summary

The aim of this study is to compare the thyroid hormone values and anti-thyroid peroxidase (anti-TPO) levels of women with a diagnosis of recurrent pregnancy loss (RPL) and healthy pregnancies. The primary objective is to find out the relationship between recurrent pregnancy loss with thyroid hormone levels and anti-TPO positivity.

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Conditions studied

  • Autoimmune Thyroiditis
  • Recurrent Miscarriage

Keywords

  • Thyroid Hormones
  • Anti Thyroid Peroxidase Antibody
  • Recurrent pregnancy loss
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In context

Thyroiditis, Autoimmune

27 studies on the registry are indexed under Thyroiditis, Autoimmune; 4 are open to participants now.

Browse Thyroiditis, Autoimmune studies →

Lead sponsor

Zonguldak Bulent Ecevit University is the lead sponsor of 100 studies on the registry; 8 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 45 Years
Sexes eligible
Female
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

The study was carried out with a total of 103 patients by retrospectively examining the patients who applied to the Gynecology and Obstetrics Clinic of Bülent Ecevit University Faculty of Medicine between 2018-2022

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • women with 2 or more pregnancy loses
  • for controls women with least one healthy baby

Exclusion criteria

Exclusion Criteria:

  • any other metabolic disease
  • women with one miscarriage
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Study design

Observational model
Case-control
Time perspective
Retrospective
Enrollment
103 participants (actual)
Patient registry
No

Groups and cohorts

  • Recurrent Pregnancy loss

    patients with a diagnosis of recurrent miscarriage

  • Healthy Controls

    healthy women at same age and similar demographics

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What researchers measure

Primary outcomes

  1. Anti-thyroid Peroxidase Antibodies

    presence of Anti-thyroid Peroxidase Antibodies in both groups

    Time frame: 4 years

  2. Thyroid Hormone Levels

    levels of Thyroid stimulant Hormone, Thyroxin and triiodothyronine levels

    Time frame: 4 years

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Study locations

1 site
  • Zonguldak Bulent Ecevit University Faculty of Medicine
    Zonguldak, Turkey
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 11, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05680376
Responsible party
Büşra Özgen Çeviker (Resident at Family Medicine Department, Zonguldak Bulent Ecevit University) — Principal investigator
First posted
Jan 11, 2023
Start date
Jan 1, 2018
Primary completion
Oct 1, 2022
Completion
Oct 1, 2022
Last update
Jan 11, 2023

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2022. You cannot join it, but the record below documents what was studied.

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