High Intensity Interval Training in Chronic Heart Failure

Browse trials for

• Heart Failure 5,685

Study arms

• Experimental
  High intensity interval training

  Behavioral: Cardiac rehabilitation comprised aerobic exercise on a treadmill accompanied by an electrocardiogram monitoring device and a blood pressure monitor

• Active comparator
  Moderate intensity continous training

  Behavioral: Cardiac rehabilitation comprised aerobic exercise on a treadmill accompanied by an electrocardiogram monitoring device and a blood pressure monitor

• Placebo comparator
  Control

  Behavioral: Cardiac rehabilitation comprised aerobic exercise on a treadmill accompanied by an electrocardiogram monitoring device and a blood pressure monitor

Interventions

• BehavioralCardiac rehabilitation comprised aerobic exercise on a treadmill accompanied by an electrocardiogram monitoring device and a blood pressure monitor

  aerobic exercise on a treadmill (T7M, Motus, Paju, South Korea) accompanied by an electrocardiogram monitoring device (Q-Tel Rehabilitation Management System, Mortara Inc., Milwaukee, WI, USA) and a blood pressure monitor

Primary outcomes

1. Maximal or peak oxygen consumption (VO2max or VO2peak, same meaning) (kg/ml/min)

   at the end of training, from baseline to 12 weeks

   Time frame: compare baseline data with 12 weeks rehabilitation data

Secondary outcomes

1. Anaerobic threshold (kg/ml/min)

   The anaerobic threshold is the highest exercise intensity that you can sustain for a prolonged period without lactate substantially building up in your blood.

   Time frame: compare baseline data with 12 weeks rehabilitation data

2. 6minute walk test (meter)

   Time frame: compare baseline data with 12 weeks rehabilitation data

3. maximal heart rate (bpm)

   Time frame: compare baseline data with 12 weeks rehabilitation data

4. systolic blood pressure (mmHg)

   Time frame: compare baseline data with 12 weeks rehabilitation data

5. diastolic blood pressure (mmHg)

   Time frame: compare baseline data with 12 weeks rehabilitation data

6. resting heart rate (bpm)

   Time frame: compare baseline data with 12 weeks rehabilitation data

7. diastolic blood presure (mmHg)

   Time frame: compare baseline data with 12 weeks rehabilitation data

8. depression scale by Patient Health Questionnaire

   Patient Health Questionnaire (PHQ; range, 0-27; higher score = severe depression; cut-off score of 5 for minimal depression)

   Time frame: compare baseline data with 12 weeks rehabilitation data

9. anxiety scale by Generalized Anxiety Disorder Scale

   Generalized Anxiety Disorder Scale (GAD; range, 0-21; higher score = severe anxiety; cut-off score of 5 for mild anxiety)

   Time frame: compare baseline data with 12 weeks rehabilitation data

10. fatigue scale by fatigue severity scale

    fatigue severity scale (FSS; range, 9-63; higher score = severe fatigue; cut-off score of 4 for fatigue)

    Time frame: compare baseline data with 12 weeks rehabilitation data

11. Quality of Life (QoL) questionnaire (MacNew)

    MacNew QoL questionnaire is a measurement tool for patients with cardiac disease that measures physical, emotional, and social functional levels to provide overall QoL.

    Time frame: compare baseline data with 12 weeks rehabilitation data