An observational study in Metastatic Prostate Carcinoma, Stage IIIB Prostate Cancer AJCC v8 and Stage IIIC Prostate Cancer AJCC v8, sponsored by Thomas Jefferson University. Recruiting at 1 site in United States. Open to male participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-05-15.
Sponsored by Thomas Jefferson University · Observational
This trial evaluates whether a network of peer genetic coaches is useful for addressing disparities in genetic testing and screening among African American men with prostate cancer that has spread from where it first started (primary site) to other places in the body (metastatic). While genetic testing has become central to prostate cancer care, African American men are less likely seek testing due to lack of awareness, cultural beliefs, financial limitations, fear of discrimination, and mistrust in the healthcare system. A network of peer genetic coaches may help address barriers, beliefs, and needs of African American men in the community and provide navigation to increase engagement in genetic testing.
PRIMARY OBJECTIVES:
I. Identify and train 6 African American (AA) men as peer genetic coaches (PGCs) for the Extending Prostate Genetic Awareness, Navigation, and Delivery (EXPAND) Network. (Train peer genetic coaches) II. Conduct a feasibility study of peer genetic coaching. (Provide individual coaching)
SECONDARY OBJECTIVE:
I. Patient-related outcomes will include change in decisional conflict for genetic counseling, acceptability/attitude toward genetic counseling and testing, and change of genetics knowledge.
OUTLINE:
AIM 1: Peer genetic coaches undergo training and education on study.
AIM 2: Patients receive an educational booklet and attend a discussion with a peer genetic coach on study.
6,370 studies on the registry are indexed under Prostatic Neoplasms; 1,400 are open to participants now.
This study's planned enrollment of 30 is below the median of 200 across 1,181 observational studies indexed under Prostatic Neoplasms.
Browse Prostatic Neoplasms studies →Thomas Jefferson University is the lead sponsor of 384 studies on the registry; 71 are open to participants now.
Of its 44 completed or terminated interventional studies of FDA-regulated products, 20 (45%) have results posted.
Counted across the registry records on this site, refreshed daily.
Men who have experience with both prostate cancer (PCA) and genetic counseling and testing, as well as peer education or navigation experience. African American men with a history of prostate cancer or with a strong family history of prostate cancer, breast cancer, ovarian cancer, pancreatic cancer, colorectal cancer, uterine cancer, renal cancer, urothelial cancer, or upper bowel cancer.
Exclusion Criteria:
AIM 1: Peer genetic coaches undergo training and education on study. AIM 2: Patients receive an educational booklet and attend a discussion with a peer genetic coach on study.
Behavioral: Training and Education · Other: Educational Intervention · Procedure: Discussion
Undergo training and education
Receive educational booklet
Also known as: Education for Intervention, Intervention by Education, Intervention through Education, Intervention, Educational
Attend discussion with peer genetic coach
Also known as: Discuss
Number of inquiries to the central number (feasibility)
Time frame: Up to 1 year
Percent of callers screened and eligible to participate (feasibility)
Time frame: Up to 1 year
Percent of eligible callers who enroll in the study (feasibility)
Time frame: Up to 1 year
Percent who complete the endpoint assessment (feasibility)
Time frame: Up to 1 year
Number and percent of men making genetic counseling appointments
Time frame: Up to 1 year
Change in decisional conflict for genetic counseling
Reported with mean and standard deviation.
Time frame: Baseline up to 1 year
Change in acceptability/attitude toward genetic counseling and testing
Reported with mean and standard deviation.
Time frame: Baseline up to 1 year
Change of genetics knowledge
Reported with mean and standard deviation
Time frame: Baseline up to 1 year
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
Contact study teamGet an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Thomas Jefferson University