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Not yet recruitingNCT05617846Updated Jan 18, 2024

Application of Antiosteoporosis Therapy in Osteolysis

An observational study in Limb; Fusion and Complication, sponsored by Henan Cancer Hospital. Not yet recruiting at 1 site in China. Per ClinicalTrials.gov, last updated 2024-01-18.

Sponsored by Henan Cancer Hospital · Observational

Study type
Observational
Model
Other
Time perspective
Prospective
Enrollment
100
Sex
All
01

Study summary

To report the postoperative complications and limb function of patients with osteolysis after surgery for bone tumors of the extremities who received anti-osteoporosis therapy in Henan Cancer Hospital in the next 10 years.

Read the detailed description

A total of 100 patients with osteolysis after surgery for bone tumors of the four extremities who received anti-osteoporosis treatment in Henan Cancer Hospital in the next 10 years were reported. The basic information, treatment methods, postoperative complications and limb function of these patients were collected.

02

Conditions studied

  • Limb; Fusion
  • Complication
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In context

Lead sponsor

Henan Cancer Hospital is the lead sponsor of 228 studies on the registry; 130 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients receiving antiosteoporosis therapy for osteolysis after surgery for bone tumors in the extremities

Inclusion criteria

  1. No age restriction, male or female.
  2. A subtype of bone tumor (including benign, malignant, and metastatic cancer) was confirmed in the pathology department of the research institution.
  3. Received excision of bone tumor in research institution.

Exclusion criteria

Exclusion Criteria:

Not applicable.

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Study design

Observational model
Other
Time perspective
Prospective
Enrollment
100 participants (estimated)
Patient registry
No

Groups and cohorts

  • Intervention group

    Patients who received antiosteoporosis therapy after bone tumor resection

    Other: Anti-osteoporosis therapy

  • Control group

    Patients who underwent bone tumor resection without antiosteoporosis therapy

Interventions

  • OtherAnti-osteoporosis therapy

    Bone healing, limb function, and complications of postoperative osteolysis in patients with bone tumors of the extremities treated with anti-osteoporosis therapy.

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What researchers measure

Primary outcomes

  1. Complications

    The incidence of complications after anti-osteoporosis treatment was collected and the severity of complications was evaluated according to CTCAE5.0.

    Time frame: Collected from the beginning of treatment to 24 months after treatment.

  2. Limb function

    Limb function was assessed using the Musculoskeletal Oncology Society (MSTS) scoring scale for seven items, namely movement, pain, stability, deformity, strength, functional activity, and emotional receptiveness. The highest possible score is 35, with 5 points allocated to each project.

    Time frame: Collected from the beginning of treatment to 24 months after treatment.

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Study locations

1 site
  • Department of Bone and Soft Tissue ,Henan Cancer Hospital
    Zhengzhou, Henan, China
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 18, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05617846
Lead sponsor
Henan Cancer Hospital
Responsible party
Wang Jiaqiang (associate chief physician, Henan Cancer Hospital) — Principal investigator
First posted
Nov 16, 2022
Start date
Dec 28, 2024 (estimated)
Primary completion
Nov 30, 2032 (estimated)
Completion
Nov 30, 2032 (estimated)
Last update
Jan 18, 2024

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Aug 2023. You cannot join it, but the record below documents what was studied.

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