An observational study in Drug Use, sponsored by Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer. Completed at 83 sites in 4 countries. Per ClinicalTrials.gov, last updated 2026-07-07.
Sponsored by Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer · Observational
Environmental awareness is leading medical field to question its responsibility and possibilities for action.
Drug residues can have a major environmental impact as per their bioaccumulation, toxicity and persistence characteristics, depending on where they are discarded. In France, drug residues should be disposed of by incineration, but in practice this is not systematic. Moreover, data on drug wastage in the operating rooms by anesthesia department are rare.
The GAME-OvBLOC observational study aim to evaluate drug wastage in the operating rooms by anesthesia department in France and to propose ways of improving health care practices.
Observational study with data collection over a 24-hour business day. Data collected refer to healthcare team's practices and patients.
Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer is the lead sponsor of 78 studies on the registry; 20 are open to participants now.
Counted across the registry records on this site, refreshed daily.
All patients who will need an anesthesia act in operating room during a 24 hours period
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Patient's data and data relating to prepared/administrated/discarded injectable drugs will be collected during 24 hours in the operating rooms by anesthesia department
Other: Quantification of injectable drugs wastage
Drugs are prescribed at discretion of physicians. For each patient who have anesthesia in the operating room, all labelled syringes having contained drugs (name + dilution) are collected and analyzed.
Ratio of overall wastage in milliliter (mL) of prepared and discarded injectable drugs, to overall volume in milliliter (mL) of prepared injectable drugs
Wastage is defined as : any prepared and unused drug that remains in syringe
Time frame: 24 hours
Reason for discarding drug residues
The reason of waste full syringe will be noticed : 1/ prepared in advance and not used ; 2/ prescription change ; 3/ preparation error ; 4/ other reason
Time frame: 24 hours
Describe drug wastage for each kind of surgery/anesthesia
Drug wastage according to type of surgery and anaesthesia
Time frame: 24 hours
Drug residues discarding process
Questionnaire on nursing practices on the choice of waste disposal circuits according to drugs
Time frame: 24 hours
Cost of overall injectable drugs wastage
Estimated cost of drug residues will be evaluated for each drug by the following formula : volume of discarded injectable drugs x theoretical price
Time frame: 24 hours
Describe drug wastage for each age group
Drug wastage according to the following age groups : adult (≥18 years old) and pediatrics (\< 1 year old, 1-5 years old, ≥ 6 years old)
Time frame: 24 hours
Describe waste and environmental impact of used plastic syringes
Number and volume of used syringes, use of pre-filled syringes, refilling of syringes and multi-patient use. Environmental impact is indirectly assessed by type of plastic used and the transport distance from the production site to France.
Time frame: 24 hours
Use of alternative to injectable drugs
Alternatives : local anaesthesia and anaesthetic gases
Time frame: 24 hours
Plan to share: No
Ran from Apr 2023 to primary completion in Jul 2023, 3 months.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.
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Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer