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Status unknownNCT05607251Updated Nov 7, 2022

Salivary Alkaline Phosphatase as a Biomarker for Dental Caries in A Group of Egyptian Children With Different Growth Rates: A Descriptive Cross-Sectional Study

An observational study in Dental Caries in Children, sponsored by Cairo University. Status unknown. Open to participants aged 6 Years to 8 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-11-07.

Sponsored by Cairo University · Observational

The sponsor has not verified this record recently (last verified Nov 2022), so the status shown — last known as Not yet recruiting — may be out of date.
Study type
Observational
Model
Other
Time perspective
Cross-sectional
Enrollment
21
Ages
6 Years to 8 Years
Sex
All
01

Study summary

Aim of the study:

  1. Assess the correlation between salivary alkaline phosphatase levels and dental caries.
  2. Assess the effect of growth of children on the levels of salivary alkaline phosphatase enzyme.
  3. Assess the effect of growth of children on caries experience and severity.
02

Conditions studied

  • Dental Caries in Children

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03

In context

Dental Caries

1,109 studies on the registry are indexed under Dental Caries; 197 are open to participants now.

This study's planned enrollment of 21 is below the median of 180 across 177 observational studies indexed under Dental Caries.

Browse Dental Caries studies →

Lead sponsor

Cairo University is the lead sponsor of 4,780 studies on the registry; 1,427 are open to participants now.

Of its 36 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
6 Years to 8 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

Children aged between 6-8 years.

Inclusion criteria

  • Children aged 6 to 8 years old.
  • Children with and without previous dental visits.

Exclusion criteria

Exclusion Criteria:

  • Children with any systemic or mental illness.
  • Children whose parents refuse to sign the informed consent.
  • Children who will not cooperate on participation
05

Study design

Observational model
Other
Time perspective
Cross-sectional
Enrollment
21 participants (estimated)
Patient registry
No

Interventions

  • OtherNo intervention

    There is no intervention as this is an observational study

06

What researchers measure

Primary outcomes

  1. Salivary Alkaline Phosphatase levels in children with and without dental caries

    Measured by spectrophotometry (unit: U/L)

    Time frame: 2 months

Secondary outcomes

  1. Caries index

    Measured by DMFT and deft (unit: scores)

    Time frame: 2 months

  2. Caries severity

    Measured by ICDAS (unit: scores)

    Time frame: 2 months

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 7, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05607251
Lead sponsor
Cairo University
Responsible party
Salma Ahmed Abdelrahman (General Dentist, Cairo University) — Principal investigator
First posted
Nov 7, 2022
Start date
Jan 2023 (estimated)
Primary completion
Mar 2023 (estimated)
Completion
Apr 2023 (estimated)
Last update
Nov 7, 2022

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Nov 2022. You cannot join it, but the record below documents what was studied.

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Discussion

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