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No longer availableNCT05582083Updated Nov 8, 2023

Managed Access Program for Momelotinib in Myelofibrosis

An expanded access record providing Momelotinib in Myelofibrosis and Primary Myelofibrosis, sponsored by GlaxoSmithKline. No longer available. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2023-11-08.

Sponsored by GlaxoSmithKline · Expanded access

Study type
Expanded access
Access type
Individual patients
Ages
18 Years and older
Sex
All
01

Study summary

Compassionate use access to Momelotinib/GSK3070785 for eligible participant with diagnosis of intermediate or high-risk myelofibrosis (MF), including primary myelofibrosis (PMF) or secondary myelofibrosis (post- polycythemia vera/ essential thrombocytopenia (PV/ET)), with anemia.

02

Conditions studied

  • Myelofibrosis
  • Primary Myelofibrosis

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Keywords

  • Momelotinib
  • GSK3070785
03

In context

Primary Myelofibrosis

431 studies on the registry are indexed under Primary Myelofibrosis; 118 are open to participants now.

Browse Primary Myelofibrosis studies →

Lead sponsor

GlaxoSmithKline is the lead sponsor of 3,647 studies on the registry; 118 are open to participants now.

Of its 264 completed or terminated interventional studies of FDA-regulated products, 239 (91%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Written informed consent can be obtained from the patient or legally authorised representative as per local regulations
  • Diagnosis of intermediate or high-risk myelofibrosis (MF), including primary myelofibrosis (PMF) or secondary myelofibrosis (post- polycythemia vera/ essential thrombocytopenia (PV/ET)), with anemia
  • 18 years or older (at the time consent is obtained)
  • The patient is willing to abide by the contraception requirements.
  • No known hypersensitivity to momelotinib, its metabolites, or any of the formulation excipients

Exclusion criteria

Exclusion Criteria:

  • Pregnant or breastfeeding female
05

Access details

Study type
Expanded access
Access type
Individual patients

Available treatment

  • Momelitinib available as tablets.

    Also known as: GSK3070785

06

Where to request access

No study locations are listed for this record.

07

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 8, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
08

Registry details

Key details

Study ID
NCT05582083
Lead sponsor
GlaxoSmithKline
Responsible party
Sponsor
First posted
Oct 17, 2022
Last update
Nov 8, 2023

Study contacts

GSK Clinical Trials
study director · GlaxoSmithKline
View the source record on ClinicalTrials.gov ↗

Requesting access

Expanded access is arranged between your doctor and the company. Ask your care team to contact the provider listed on this record.

No contact was published for this record. The registry link below has the sponsor’s details.

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Discussion

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