An expanded access record providing Balstilimab and Zalifrelimab in Cancer, sponsored by Agenus Inc.. Available at 7 sites in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-11-04.
Sponsored by Agenus Inc. · Expanded access
This is an expanded access study for cancer treatment with balstilimab alone or in combination with zalifrelimab for an intermediate-size participant population. This study addresses the treatment needs of participants who have been previously and specifically treated with balstilimab alone or in combination with zalifrelimab in a clinical study, who have experienced a benefit from this treatment and/or wish to continue treatment, and who are eligible for treatment under this expanded access study.
This study will not exceed 100 participants. Participants will be reevaluated annually to assess the treatment benefit of zalifrelimab and/or balstilimab and thereby, continued eligibility for treatment. Under this program, treatment will be continued with balstilimab, as either monotherapy or as used in combination therapy with zalifrelimab, for participants that have previously received one or both of these investigational medicinal products in a clinical study.
10,818 studies on the registry are indexed under Neoplasms; 2,324 are open to participants now.
Browse Neoplasms studies →Agenus Inc. is the lead sponsor of 31 studies on the registry; 2 are open to participants now.
Of its 11 completed or terminated interventional studies of FDA-regulated products, 3 (27%) have results posted.
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Exclusion Criteria:
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An anti-programmed death 1 (PD-1) monoclonal antibody.
Also known as: AGEN2034
An anti-cytotoxic T-lymphocyte antigen 4 (CTLA-4) monoclonal antibody.
Also known as: AGEN1884
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
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