An interventional study of Coconut oil and Palm oil in Lipemia, sponsored by University of Jordan. Completed at 2 sites in Jordan. Open to participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-08-29.
Sponsored by University of Jordan · Not applicable, Interventional, and Treatment
The main objective is to investigate if foods high in coconut oil (MCFA) or palm oil (LCFA) have different impacts on postprandial blood lipid levels and appetite via a visual analog scale (VAS).
Postprandial lipemia has been recognized as a cardiovascular disease risk factor. The rate of postprandial triglyceride production and clearance in the blood, as well as the appetite, are influenced by the quality of the food consumed, such as the length of saturated fatty acids. The study will include 24 healthy adults ranging in age from 18 to 40 years old, of both sexes and it will be conducted at the University of Jordan. The study will involve two experimental test days, each separated by at least a week of washout interval, and each test day will last for 6 hours. All subjects will be randomly assigned to one of the experimental meals using computer-generated tables. Blood serum samples (2 mL) will be taken after an overnight fast and 2, 4, and 6 hours after eating the meals, and blood lipid profiles [total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglyceride (TG)] will be examined in a private lab. After that, participants will be allowed an ad libitum intake of standard meals. Each meal will be weighed before and after it is consumed, with the amount of food ingested being calculated.
839 studies on the registry are indexed under Hyperlipidemias; 107 are open to participants now.
This study's enrollment of 26 is below the median of 88 across 707 interventional studies indexed under Hyperlipidemias.
Browse Hyperlipidemias studies →University of Jordan is the lead sponsor of 130 studies on the registry; 20 are open to participants now.
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Exclusion Criteria:
The coconut oil will be given to each participant in the amount of 40 g, which will be incorporated into biscuits. Each participant will have ten minutes to consume biscuits with 250 ml of water. No other food will be consumed during the study period (6 hours). After that, participants will be allowed an ad libitum intake of standard meals. Each meal will be weighed before and after it is consumed, with the amount of food ingested being calculated. Then the participants will take the other treatment after a 1-week washout interval.
Dietary Supplement: Coconut oil
The palm oil will be given to each participant in the amount of 40 g, which will be incorporated into biscuits. Each participant will have ten minutes to consume biscuits with 250 ml of water. No other food will be consumed during the study period (6 hours). After that, participants will be allowed an ad libitum intake of standard meals. Each meal will be weighed before and after it is consumed, with the amount of food ingested being calculated. Then the participants will take the other treatment after a 1-week washout interval.
Dietary Supplement: Palm oil
Coconut oil will be given to each participant in the amount of 40 g, which will be incorporated into biscuits.
Palm oil will be given to each participant in the amount of 40 g, which will be incorporated into biscuits.
Anthropometric measurements ( Height)
Standing height, without footwear, will be taken using stadiometer to the nearest 5mm
Time frame: baseline, pre-intervention, 1 day for each participant /during 3 months
Anthropometric measurements (Weight)
Bioelectrical impedance will be used to determine body weight
Time frame: baseline, pre-intervention, 1 day for each participant /during 3 months
Anthropometric measurements (waist circumference)
Waist circumference (WC) will be measured at the midway between the lowest ribs and the iliac crest using a standard tape to the nearest 1 cm
Time frame: baseline, pre-intervention, 1 day for each participant /during 3 months
Anthropometric measurements (percentage body fat)
Bioelectrical impedance will be used to determine body composition
Time frame: baseline, pre-intervention,1 day for each participant /during 3 months
Biochemical measurements (Total cholesterol (TC))
Up to 6 hours
Time frame: After the intervention / up to 3 months from collecting the samples
Biochemical measurements (Low density lipoprotein cholesterol (LDL))
Low-density lipoprotein cholesterol test will be performed after an overnight fast and 2, 4, and 6 hours after eating the meals
Time frame: Up to 6 hours
Biochemical measurements ( High density lipoprotein cholesterol (HDL))
High-density lipoprotein cholesterol test will be performed after an overnight fast and 2, 4, and 6 hours after eating the meals
Time frame: Up to 6 hours
Biochemical measurements (Triglyceride (TG))
Triglyceride test will be performed after an overnight fast and 2, 4, and 6 hours after eating the meals
Time frame: Up to 6 hours
Dietary intake (3-days food record)
Participants will be asked to fill out a food record to track changes in their (intake) appetite
Time frame: one day
Plan to share: No
This study is completed, as verified in Aug 2023. You cannot join it, but the record below documents what was studied.
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Studies of the drugs tested here: Coconut Oil · Palm Oil