An interventional study of Resistive Breathing Training group and inspiratory hold technique in Chronic Bronchitis, sponsored by Riphah International University. Status unknown at 1 site in Pakistan. Open to participants aged 45 Years to 60 Years. Per ClinicalTrials.gov, last updated 2022-09-09.
Sponsored by Riphah International University · Not applicable, Interventional, and Treatment
The aim of the study is to determine the importance and impact of resistive breathing techniques versus inspiratory hold techniques in patients with chronic bronchitis and specially to find out if there are any changes seen in results measured via the incentive spirometer.
Chronic Bronchitis (CB) is defined as a chronic cough and sputum production for at least 3 months a year for 2 consecutive years. It is covered under the umbrella term of Chronic Obstructive Pulmonary Disease (COPD). Chronic bronchitis is thought to be caused by overproduction and hypersecretion of mucus by goblet cells. Epithelial cells lining the airway response to toxic, infectious stimuli by releasing inflammatory mediators and e.g. pro-inflammatory cytokines. During an acute exacerbation of chronic bronchitis, the bronchial mucous membrane becomes hyperemic and edematous with diminished bronchial mucociliary function. This, in turn, leads to airflow impediment because of
luminal obstruction to small airways. The airways become clogged by debris and this further increases the irritation. The characteristic cough of bronchitis is caused by the copious secretion of mucus in chronic bronchitis. Pseudostratified epithelium, highlighting the pseudostratified epithelial cells, goblets cells (shown in blue), then underlying connective tissue.(3) To determine the importance and impact of resistive breathing techniques versus inspiratory hold techniques in patients with chronic bronchitis and specially to find out if there are any changes seen in results measured via incentive spirometer. There are few studies done over it whereas purpose of this research work is to compare these techniques to get better results.
209 studies on the registry are indexed under Bronchitis, Chronic; 14 are open to participants now.
This study's planned enrollment of 26 is below the median of 101 across 154 interventional studies indexed under Bronchitis, Chronic.
Browse Bronchitis, Chronic studies →Riphah International University is the lead sponsor of 2,193 studies on the registry; 650 are open to participants now.
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Diagnosed with chronic bronchitis
Exclusion Criteria:
Presence of any genetic disorders (cystic fibrosis).
The patients performed two sessions each of 15 minutes session of resistive breathing for four days a week for six weeks using an inspiratory resistive device. Ask patient to take long slow inspirations while breathing through the resistive device
Other: Resistive Breathing Training group
With the patient in a comfortable position such as side lying or reclined, the therapist may assist the patient by placing both hands on abdominal area to provide proprioceptive feedback. Then in a relaxed tone of voice therapist instructs the patient to sniff quickly through the nose three times with slow, relaxed exhalations
Other: inspiratory hold technique
The patients performed two sessions each of 15 minutes session of resistive breathing for four days a week for six weeks using an inspiratory resistive device. Ask patient to take long slow inspirations while breathing through the resistive device
With the patient in a comfortable position such as side lying or reclined, the therapist may assist the patient by placing both hands on abdominal area to provide proprioceptive feedback. Then in a relaxed tone of voice therapist instructs the patient to sniff quickly through the nose three times with slow, relaxed exhalations
oxygen saturation
amount of oxygen traveling through your body with your red blood cells. Changes will be assessed at baseline, 3rd week and 6th weeks measured
Time frame: Changes will be assessed at baseline, 3rd week and 6th weeks measured
Forced expiratory volume in one second
amount of air expired in first one second. Changes will be assessed at baseline, 3rd week and 6th weeks measured
Time frame: Changes will be assessed at baseline, 3rd week and 6th weeks measured
Forced vital capacity
the total amount of air exhaled during the FEV test. Changes will be assessed at baseline, 3rd week and 6th weeks measured
Time frame: Changes will be assessed at baseline, 3rd week and 6th weeks measured
FEV1/FVC ratio
the amount of air exhaled in the first second divided by all of the air exhaled during a maximal exhalation.
Time frame: 6 weeks
shortness of breath measured through borge scale of dyspnea
shortness of breath. Changes will be assessed at baseline, 3rd week and 6th weeks measured
Time frame: Changes will be assessed at baseline, 3rd week and 6th weeks measured
SGRQ questionnaire
how breathing problems effects quality of life . Changes will be assessed at baseline, 3rd week and 6th weeks measured
Time frame: Changes will be assessed at baseline, 3rd week and 6th weeks measured
Plan to share: No
This study is status unknown, as verified in Sep 2022. You cannot join it, but the record below documents what was studied.
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