An interventional study of Dry Needling and PRP in Temporomandibular Joint Disc Displacement, sponsored by Postgraduate Institute of Dental Sciences Rohtak. Status unknown at 1 site in India. Open to participants aged 18 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-09-08.
Sponsored by Postgraduate Institute of Dental Sciences Rohtak · Not applicable, Interventional, and Treatment
Pain and trismus are of the prime concerns for the patients in case of Anterior disc displacement ADD of temporomandibular joint (TMJ). In the recent times, PRP has has produced promising results in management of TMDs. It has potential healing properties on new bone and cartilage through the recruitment, proliferation, migration, and differentiation of cells and its tissue remodelling, matrix production, and chondrogenic differentiation properties. It also increases the production of hyaluronic acid by synoviocytes. Needle injury also produces immediate analgesia without hypesthesia, mainly on the painful spot making it effective for the pain reduction and improved mouth opening. Similar effect of dry needling can also be expected in the joint space where it may induce a transient inflammatory cascade leading to healing of the damaged tissue.
So, the Present study is designed to evaluate the efficacy of PRP for the treatment of ADD of TMJ.
Study Design: Randomized clinical trial Study Duration: This study will be completed in 1 year 3 months (3 months for patient recruitment, 9 months for study including treatment and follow up and 3 months for data compilation).
Population: Patients suffering from Anterior Disc Displacement will be recruited in study from regular OPD of the Department of Oral Medicine and Radiology.
Sample size: Sample size consists of 39 patients in each group. Methods: PRP will be performed in test group while dry needling will be performed in control group.
Postgraduate Institute of Dental Sciences Rohtak is the lead sponsor of 209 studies on the registry; 71 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Patients diagnosed with ADD under this group are subjected to Dry Needling
Procedure: Dry Needling
Patients diagnosed with ADD under this group are administered with 1ml of PRP solution .
Procedure: PRP
Dry Needling will be done for the patients with ADD of TMJ in the retrodiscal tissue and superior joint space .
Patients with ADD are administered with 1ml of PRP into the retrodiscal tissue and the superior joint space. PRP will be prepared by method proposed by Okuda et al., 2003. Reinjection will be given after 2 weeks if required.
Pain intensity
To evaluate the intensity of pain before and after the treatment (Visual Analogue Scale score).
Time frame: 2 weeks
Pain intensity
To evaluate the intensity of pain before and after the treatment (Visual Analogue Scale score).
Time frame: 4 weeks
Pain intensity
To evaluate the intensity of pain before and after the treatment (Visual Analogue Scale score).
Time frame: 3 months
Pain intensity
To evaluate the intensity of pain before and after the treatment (Visual Analogue Scale score).
Time frame: 6 months
Mouth opening and Functional movements
To evaluate the maximal mouth opening and functional movements before and after the treatment (millimetre).
Time frame: 2 weeks
Mouth opening and Functional movements
To evaluate the maximal mouth opening and functional movements before and after the treatment (millimetre).
Time frame: 4 weeks
Mouth opening and Functional movements
To evaluate the maximal mouth opening and functional movements before and after the treatment (millimetre).
Time frame: 3 months
Mouth opening and Functional movements
To evaluate the maximal mouth opening and functional movements before and after the treatment (millimetre).
Time frame: 6 months
Joint sounds
To evaluate the changes in joint sounds before and after the treatment (present or absent ).
Time frame: 2 weeks
Joint sounds
To evaluate the changes in joint sounds before and after the treatment (present or absent ).
Time frame: 4 weeks
Joint sounds
To evaluate the changes in joint sounds before and after the treatment (present or absent ).
Time frame: 3 months
Joint sounds
To evaluate the changes in joint sounds before and after the treatment (present or absent ).
Time frame: 6 months
Pain medication
To evaluate the need for pain medicine utilization (number of tablets).
Time frame: 2 weeks
Pain medication
To evaluate the need for pain medicine utilization (number of tablets).
Time frame: 4 weeks
Pain medication
To evaluate the need for pain medicine utilization (number of tablets).
Time frame: 3 months
Pain medication
To evaluate the need for pain medicine utilization (number of tablets).
Time frame: 6 months
Patient satisfaction
To evaluate patient satisfaction before and after treatment (Likerts scale) in both groups
Time frame: 2 weeks
Patient satisfaction
To evaluate patient satisfaction before and after treatment (Likerts scale) in both groups
Time frame: 4 weeks
Patient satisfaction
To evaluate patient satisfaction before and after treatment (Likerts scale) in both groups
Time frame: 3 months
Patient satisfaction
To evaluate patient satisfaction before and after treatment (Likerts scale) in both groups
Time frame: 6 months
Sleep pattern
To evaluate sleep pattern before and after treatment (Visual Analogue Scale score) in both groups
Time frame: 2 weeks
Sleep pattern
To evaluate sleep pattern before and after treatment (Visual Analogue Scale score) in both groups
Time frame: 4 weeks
Sleep pattern
To evaluate sleep pattern before and after treatment (Visual Analogue Scale score) in both groups
Time frame: 3 months
Sleep pattern
To evaluate sleep pattern before and after treatment (Visual Analogue Scale score) in both groups
Time frame: 6 months
Plan to share: No
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Postgraduate Institute of Dental Sciences Rohtak