CClinicalTrials.gg
Active, not recruitingNCT05522205Updated Sep 2, 2026

Regulated Cannabis Access in Basel

An interventional study of Regulated cannabis access in pharmacies in Cannabis Use Disorder, Mental Health Disorder and Physical Illness, sponsored by Health Department of the Canton of Basel-Stadt. Active, not recruiting at 1 site in Switzerland. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-02.

Sponsored by Health Department of the Canton of Basel-Stadt · Not applicable, Interventional, and Other

Phase
Not applicable
Study type
Interventional
Enrollment
374
Allocation
Randomized
Ages
18 Years and older
Sex
All
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Study summary

The randomised controlled study on regulated cannabis access in pharmacies in Basel aims to investigate the effects of regulated cannabis access on consumption behaviour and mental and physical health in comparison to the illegal market.

Read the detailed description

This project consist of two parts: The first part is a randomised controlled study, the second part is an observational study. The randomised controlled study will last six months. Participants will randomly be assigned to one of two groups: Group 1 has immediately access to regulated cannabis in pharmacies; Group 2 has to wait for six months. After six months all participants will have access to regulated cannabis in pharmacies (oberservational study). Every six month participants will be invited to answer online-questionnaires on their cannabis consumption behavior, their mental and physical health. The entire study lasts 2.5 years.

02

Conditions studied

  • Cannabis Use Disorder
  • Mental Health Disorder
  • Physical Illness

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Keywords

  • cannabis regulation
  • health effects
  • cannabis consumption
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In context

Mental Disorders

2,107 studies on the registry are indexed under Mental Disorders; 416 are open to participants now.

This study's enrollment of 374 is above the median of 94 across 1,574 interventional studies indexed under Mental Disorders.

Browse Mental Disorders studies →

Lead sponsor

This is the only study on the registry with Health Department of the Canton of Basel-Stadt as lead sponsor.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • At least 18 years, residence in Basel-Stadt, consuming cannabis at least monthly during the last 6 months (positive urine sample)

Exclusion criteria

Exclusion Criteria:

  • pregnant or breastfeeding, currently suicidal, currently psychotic, current inpatient psychiatric treatment
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Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
374 participants (actual)

Study arms

  • Experimental
    Experimental group

    Immediately regulated cannabis access in pharmacies.

    Other: Regulated cannabis access in pharmacies

  • No intervention
    Control group

    During the first six months participants of the control group have to continue to buy their cannabis on the illicit market. Afterthese six months they also have access to regulated cannabis access.

Interventions

  • OtherRegulated cannabis access in pharmacies

    The study does not investigate the health effects of cannabis. The study investigates the effects of regulated cannabis access on cannabis consumption and health in comparison to the unregulated illegal market.

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What researchers measure

Primary outcomes

  1. Change in problematic cannabis consumption behaviour

    Cannabis Use Disorder Identification Test - Revised; min. value 0, max. value 32; higher scores mean worse outcome

    Time frame: 6 / 12 /18 /24 / 30 months

Secondary outcomes

  1. Change in depression

    Patient Health Questionnaire; min. value 0, max. value 27; higher scores mean worse outcome

    Time frame: 6 / 12 /18 /24 / 30 months

  2. Change in anxiety

    Generalized Anxiety Disorder; min. value 0, max. value 21; higher scores mean worse outcome

    Time frame: 6 / 12 /18 /24 / 30months

  3. Change in psychosis

    Checklist of early intervention; min. value 0, max. value 8; higher scores mean worse outcome

    Time frame: 6 / 12 /18 /24 / 30 months

  4. Change in physical health

    Symptom Checklist - 90, Somatization; min. value 0, max. value 48; higher scores mean worse outcome

    Time frame: 6 / 12 /18 /24 / 30 months

07

Study locations

1 site
  • Canton Basel-Stadt
    Basel, Canton of Basel-City, Switzerland
08

References and documents

Publications

  • Baltes-Flueckiger L, Steinauer R, Meyer M, Vogel M, Walter M. Effects of cannabis regulation in Switzerland: Study protocol of a randomized controlled trial. Front Psychiatry. 2023 Mar 23;14:1139325. doi: 10.3389/fpsyt.2023.1139325. eCollection 2023. PubMed 37032954 ↗

Individual participant data

Plan to share: Yes — All IPD that underlie results in publications.

Supporting information: Sap, Icf

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 2, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05522205
Lead sponsor
Health Department of the Canton of Basel-Stadt
Collaborators
University of Basel, University Psychiatric Clinics Basel, Psychiatric Services Aargau AG
Responsible party
Marc Walter (Prof. Dr. med., Psychiatric Services Aargau AG) — Principal investigator
First posted
Aug 30, 2022
Start date
Jan 31, 2023
Primary completion
Jan 31, 2027 (estimated)
Completion
Jan 31, 2027 (estimated)
Last update
Sep 2, 2026

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.

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