An interventional study of corneal neurotomy in Reduced Corneal Sensation, sponsored by Iran University of Medical Sciences. Completed at 1 site in Iran, Islamic Republic of. Per ClinicalTrials.gov, last updated 2022-08-10.
Sponsored by Iran University of Medical Sciences · Not applicable, Interventional, and Prevention
During conjunctival flap surgery the corneal epithelium is removed and a conjunctival flap is placed on the cornea and after a few weeks the conjunctiva covers the surface of the eye.
Complications of this operation are flap retraction, conjunctival inclusion cysts, bleeding, infection and pain. Pain is one of the main complications of conjunctival flap surgery. Two sources are conceivable for pain: 1) conjunctival pain 2) corneal pain, the second of which is the main part of the pain.
Numerous methods for controlling corneal pain have been reported in various articles. Eye patches are often recommended for the treatment of corneal abrasions despite the lack of evidence. Recommended analgesics to control corneal scratch pain include nonsteroidal anti-inflammatory drugs (NSAIDs), local anesthetics, and topical cycloplegias.
In this article, we are going to review and evaluate a new method called corneal neuorotomy, i.e., corneal nerve endings that inserted radially can be cut to reduce postoperative pain.
The main idea of this randomized clinical trial is to test the extent of pain relief after incision of radial corneal nerve endings.
Patients are divided into two groups. In the first group, the same classic method of conjunctival flap surgery was used and in the second group, conjunctival flap surgery was performed adjuncted by cutting the radial superficial nerves of the cornea. The postoperative pain scores of these two groups will be measured using visual analogue scale, after 6 hours, 24 hours and 48 hours, and finally the average pain of the two groups will be compared.
5,093 studies on the registry are indexed under Pain, Postoperative; 1,140 are open to participants now.
This study's enrollment of 9 is below the median of 75 across 4,344 interventional studies indexed under Pain, Postoperative.
Browse Pain, Postoperative studies →Iran University of Medical Sciences is the lead sponsor of 24 studies on the registry; 7 are open to participants now.
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In this first group, the same classic method of Gunderson conjunctival flap surgery will be used.
in the this group, Gunderson conjunctival flap surgery will be performed adjuncted by corneal neurotomy
Procedure: corneal neurotomy
Classic Gunderson conjunctival flap surgery adjuncted by corneal neurotomy
postoperative pain 6 hours after conjunctival flap
measured via self-reported visual analogue scale (0 -10) , higher score means more severe pain
Time frame: 6 hours after surgery
postoperative pain 24 hours after conjunctival flap
measured via self-reported visual analogue scale (0 -10) , higher score means more severe pain
Time frame: 24 hours after surgery
postoperative pain 48 hours after conjunctival flap
measured via self-reported visual analogue scale (0 -10) , higher score means more severe pain
Time frame: 48 hours after surgery
This study is completed, as verified in Aug 2022. You cannot join it, but the record below documents what was studied.
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Iran University of Medical Sciences