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CompletedNCT05490784Updated Nov 9, 2022

Effects of Lee Silverman Voice Treatment BIG on Dynamic Balance in Parkinson's Patients

An interventional study of Lee Silverman Voice Treatment BIG and conventional treatment in Parkinson Disease, Motor Disorders and Balance; Distorted, sponsored by Riphah International University. Completed at 1 site in Pakistan. Open to participants aged 40 Years to 70 Years. Per ClinicalTrials.gov, last updated 2022-11-09.

Sponsored by Riphah International University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 7 months after the study started (first participant enrolled Jan 2022, registered Aug 2022).
Phase
Not applicable
Study type
Interventional
Enrollment
26
Allocation
Randomized
Ages
40 Years to 70 Years
Sex
All
01

Study summary

To determine the effects of Lee Silverman Voice Treatment BIG on dynamic balance in Parkinson's patients

Read the detailed description

This study will be conducted to compare the effects of Lee Silverman Voice Treatment BIG and conventional physiotherapy on dynamic balance in patients of PD. Patients will be recruited according to inclusion criteria and data will be collected from Riphah rehabilitation center, National Hospital Lahore. Dynamic gait index will be used as data collection tool to test dynamic balance of patients. Patients will be allocated to intervention groups by randomization. After approval from ethical committee, data collection will be started and informed consent will be taken from all patients.

02

Conditions studied

  • Parkinson Disease
  • Motor Disorders
  • Balance; Distorted

Keywords

  • Parkinson Disease
  • Balance; Distorted
  • Motor Disorders
03

In context

Parkinson Disease

4,585 studies on the registry are indexed under Parkinson Disease; 1,097 are open to participants now.

This study's enrollment of 26 is below the median of 40 across 3,365 interventional studies indexed under Parkinson Disease.

Browse Parkinson Disease studies →

Lead sponsor

Riphah International University is the lead sponsor of 2,176 studies on the registry; 637 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
40 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Stage I, II, III Parkinson's patients on Hoehn \&;Yahr classification
  • Able to walk without assistive devices
  • Stable medication 4 weeks prior to and during study

Exclusion criteria

Exclusion Criteria:

  • Patients with depression or dementia
  • Disabling bradykinesia to make sure patients are efficient to engage and cooperate in conventional physical therapy
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
26 participants (actual)

Study arms

  • Experimental
    Lee Silverman Voice Treatment big with conventional treatment

    Lee Silverman Voice Treatment big with conventional treatment

    Other: Lee Silverman Voice Treatment BIG

  • Active comparator
    control group

    Patients assigned to control group received conventional treatment program encompassing set of exercises such as complex motor sequences, stretching, dual tasking, mental imagery and core stability.

    Other: conventional treatment

Interventions

  • OtherLee Silverman Voice Treatment BIG

    Patients assigned to experimental group will get Lee Silverman Voice Treatment BIG along with conventional treatment.

  • Otherconventional treatment

    patients in this group will get conventional treatment program encompassing set of exercises such as complex motor sequences, stretching, dual tasking, mental imagery and core stability.

06

What researchers measure

Primary outcomes

  1. Dynamic Gait Index

    Dynamic gait index assesses postural stability, gait, and balance. It evaluates various gait- related tasks with challenging situations such as head turn, speed change, obstacles and stairs climbing.

    Time frame: 9 months

07

Study locations

1 site
  • Riphah International University
    Islamabad, Fedral 44000, Pakistan
08

References and documents

Publications

  • Oguz S, Erturk G, Polat MG, Apaydin H. The effect of kinesiophobia on physical activity, balance, and fear of falling in patients with Parkinson's disease. Physiother Theory Pract. 2023 Apr;39(4):865-872. doi: 10.1080/09593985.2022.2028325. Epub 2022 Jan 18. PubMed 35042438 ↗
  • Fleming Walsh S, Balster C, Chandler A, Brown J, Boehler M, O'Rear S. LSVT BIG(R) and long-term retention of functional gains in individuals with Parkinson's disease. Physiother Theory Pract. 2022 May;38(5):629-636. doi: 10.1080/09593985.2020.1780655. Epub 2020 Jun 17. PubMed 33969801 ↗
  • Schaible F, Maier F, Buchwitz TM, Schwartz F, Hoock M, Schonau E, Libuda M, Hordt A, van Eimeren T, Timmermann L, Eggers C. Effects of Lee Silverman Voice Treatment BIG and conventional physiotherapy on non-motor and motor symptoms in Parkinson's disease: a randomized controlled study comparing three exercise models. Ther Adv Neurol Disord. 2021 Feb 18;14:1756286420986744. doi: 10.1177/1756286420986744. eCollection 2021. PubMed 33680093 ↗
  • Tremblay C, Abbasi N, Zeighami Y, Yau Y, Dadar M, Rahayel S, Dagher A. Sex effects on brain structure in de novo Parkinson's disease: a multimodal neuroimaging study. Brain. 2020 Oct 1;143(10):3052-3066. doi: 10.1093/brain/awaa234. PubMed 32980872 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 9, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05490784
Responsible party
Sponsor
First posted
Aug 8, 2022
Start date
Jan 1, 2022
Primary completion
Aug 20, 2022
Completion
Aug 20, 2022
Last update
Nov 9, 2022

Study contacts

zeest hashmi, MSNMPT
principal investigator · Riphah International University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2022. You cannot join it, but the record below documents what was studied.

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