An observational study in Duchenne Muscular Dystrophy, Lower Urinary Tract Symptoms and Muscle Weakness, sponsored by Lokman Hekim Üniversitesi. Completed at 1 site in Turkey. Open to male participants aged 5 Years to 18 Years. Per ClinicalTrials.gov, last updated 2022-07-19.
Sponsored by Lokman Hekim Üniversitesi · Observational
The aim of this study is to examine the prevalence of lower urinary tract symptoms (LUTS) in children with Duchenne Muscular Dystrophy (DMD) and the relationship between functional level, posture, muscle strength, pelvic floor muscle control, participation in activities of daily living, and quality of life that may be associated with these symptoms.
Forty-five children with DMD between the ages of 5-18 (Age: 9.00±3.32 years, Weight: 31,10±12,59 kg, Height: 125,87±18,46 cm) and their families were included in the study. LUTS was assessed with Dysfunctional Voiding And Incontinence Scoring System, functional level with Brooke Upper Extremity Functional Classification and Vignos Scale, posture with the New York Posture Assessment Questionnaire, Baseline Bubble Inclinometer (10602, Fabrication Enterprises Inc. New York, USA) and Baseline Digital Inclinometer (12-1057, Fabrication Enterprises Inc, New York, USA), participation in activities of daily living was assessed with the Barthel Index and quality of life was assessed with the Pediatric Quality of Life Inventory 3.0 Neuromuscular Module. Also, using the Hoggan microFET2 (Hoggan Scientific, LLC, Salt Lake City UT, USA) device, hip flexors, quadriceps femoris muscles, shoulder flexors, elbow extensors, elbow flexors, trunk extensors and flexors were evaluated in terms of muscle strength. Evaluations were made once, and the associated factors were compared in the group with and without LUTS, and the relationship between the factors and the severity of LUTS was examined.
548 studies on the registry are indexed under Muscular Dystrophies; 89 are open to participants now.
This study's enrollment of 45 is below the median of 69 across 179 observational studies indexed under Muscular Dystrophies.
Browse Muscular Dystrophies studies →Lokman Hekim Üniversitesi is the lead sponsor of 13 studies on the registry; 4 are open to participants now.
Counted across the registry records on this site, refreshed daily.
It consisted of children aged 5-18 years with a diagnosis of DMD and their families.
Exclusion Criteria:
Children with Duchenne Muscular Dystrophy (DMD) between the ages of 5 and 18 who were diagnosed with DMD by a specialist physician as a result of gene analysis and/or muscle biopsy and their families were included in the study.
Device: Baseline Bubble Inclinometer, Baseline Digital İnclinometer and Hoggan microFET2 devices
Bubble inclinometer was used to measure lumbar lordosis angle, Digital inclinometer was used to measure pelvic inclination angle and Hoggan microFET2 was used for muscle strength measurement.
Lower urinary system symptoms
It will be investigated how many of the children with DMD participating in the study will have lower urinary system symptoms.
Time frame: 1 hour
Lower urinary system dysfunction
It will be investigated how many of the children with DMD participating in the study will have lower urinary system dysfunction.
Time frame: 1 hour
Muscle strength and lower urinary system symptoms
It will be investigated whether there is a relationship between lower urinary tract symptoms and muscle strength in children with DMD.
Time frame: 1 hour
Functionality and lower urinary system symptoms
It will be investigated whether there is a relationship between lower urinary tract symptoms and functionality in children with DMD.
Time frame: 1 hour
Posture and lower urinary system symptoms
It will be investigated whether there is a relationship between lower urinary tract symptoms and posture in children with DMD.
Time frame: 1 hour
Pelvic floor muscle control and lower urinary system symptoms
It will be investigated whether there is a relationship between lower urinary tract symptoms and pelvic floor muscle control in children with DMD.
Time frame: 1 hour
Activities of daily living and lower urinary system symptoms
It will be investigated whether there is a relationship between lower urinary tract symptoms and activities of daily living in children with DMD.
Time frame: 1 hour
Quality of life and lower urinary system symptoms
It will be investigated whether there is a relationship between lower urinary tract symptoms and quality of life in children with DMD.
Time frame: 1 hour
Urologist evaluation
It will investigate whether children with DMD have ever been to a urologist in their life.
Time frame: 1 hour
Plan to share: Undecided
No publications or documents are linked to this record.
This study is completed, as verified in Jul 2022. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Lokman Hekim Üniversitesi