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RecruitingNCT05464251SEAUpdated Feb 13, 2026

Prospective Analysis of Spinal Epidural Abscess

An observational study in Spinal Epidural Abscess, sponsored by Francis Farhadi. Recruiting at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-02-13.

Sponsored by Francis Farhadi · Observational

From the registry’s dates

  • Started Jul 2022; still recruiting 4 years 2 months later.
Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
200
Ages
18 Years and older
Sex
All
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Study summary

This is a prospective study involving all patients treated at the University of Kentucky for spinal epidural abscess over a 2-year period. Based on ongoing referrals of patients with SEA, we expect that 200 patients will be enrolled during this time window. We propose to study all available clinical, pathological, radiological, and socioeconomic data of patients diagnosed with a spinal infection with or without a history of drug abuse over this study period. All patients' charts will be prospectively reviewed starting at the time of presentation for a period of 1 year.

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Conditions studied

  • Spinal Epidural Abscess
03

In context

Lead sponsor

Francis Farhadi is the lead sponsor of 9 studies on the registry; 7 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

This study will include all patients, over the age of 18, who will undergo treatment for spinal epidural abscess infections at the University of Kentucky during the study period.

Inclusion criteria

  • All patient with ICD codes for pyogenic vertebral osteomyelitis, discitis, and spinal epidural abscess will be reviewed for inclusion.

Exclusion criteria

Exclusion Criteria:

  • Patients unwilling or unable to attend follow up appointments.
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Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
200 participants (estimated)
Patient registry
No

Groups and cohorts

  • Subjects with spinal epidural abscess with a history of drug abuse

    Other: Prospective chart review of subjects diagnosed with spinal epidural abscess

  • Subjects with spinal epidural abscess with no history of drug abuse

    Other: Prospective chart review of subjects diagnosed with spinal epidural abscess

Interventions

  • OtherProspective chart review of subjects diagnosed with spinal epidural abscess

    Collection and assessment of available clinical, pathological, radiological, and socioeconomic data on subjects presenting with spinal epidural abscess. Standard of care treatment and outcomes for each group will be analyzed.

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What researchers measure

Primary outcomes

  1. Correlation between employment status and infection reoccurrence.

    Determine the statistical correlation between employment status and infection reoccurrence within 1 year of diagnosis.

    Time frame: 1 year

  2. Correlation between income and infection reoccurrence.

    Determine the statistical correlation between income and infection reoccurrence within 1 year of diagnosis.

    Time frame: 1 year

  3. Correlation between insurer and infection reoccurrence.

    Determine the statistical correlation between insurer (private, Medicare/Medicade and uninsured) and infection reoccurrence within 1 year of diagnosis.

    Time frame: 1 year

  4. Correlation between living situation and infection reoccurrence.

    Determine the statistical correlation between living situation (owns, rents, or homeless) and infection reoccurrence within 1 year of diagnosis.

    Time frame: 1 year

07

Study locations

1 of 1 sites recruiting
  • University of Kentucky
    Lexington, Kentucky 40536, United States
    Recruiting
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References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 13, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05464251
Lead sponsor
Francis Farhadi
Responsible party
Francis Farhadi (Associate Professor, University of Kentucky) — Sponsor-investigator
First posted
Jul 19, 2022
Start date
Jul 12, 2022
Primary completion
Jun 2027 (estimated)
Completion
Jun 2027 (estimated)
Last update
Feb 13, 2026

Study contacts

Francis Farhadi, MD, PhD
Contact
francis.farhadi@uky.edu
859-562-0247
Harshit Arora, PhD
Contact
harshit.arora@uky.edu
859-323-4533
Francis Farhadi, MD, PhD
principal investigator · University of Kentucky

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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