An observational study in Intestinal Metaplasia of Gastric Mucosa, Artificial Intelligence and Endoscopy, sponsored by Shandong University. Status unknown at 1 site in China. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2022-07-15.
Sponsored by Shandong University · Observational
Gastric intestinal metaplasia(GIM) is an important stage in the gastric cancer(GC). With technical advance of image-enhanced endoscopy (IEE), studies have demonstrated IEE has high accuracy for diagnosis of GIM. The endoscopic grading system (EGGIM), a new endoscopic risk scoring system for GC, have been shown to accurately identify a wide range of patients with GIM. However, the high diagnostic accuracy of GIM using IEE and EGGIM assessments performed all require much experience, which limits the application of EGGIM. The investigators aim to design a computer-aided diagnosis program using deep neural network to automatically evaluate the extent of IM and calculate the EGGIM scores.
Globally, gastric cancer is the fifth most prevalent malignancy and the third leading cause of cancer mortality. Gastric intestinal metaplasia (GIM) is an intermediate precancerous gastric lesion in the gastric cancer cascade. Studies have shown that the 5-year cumulative incidence of gastric cancer in IM patients ranges from 5.3% to 9.8% . With technical advance of image-enhanced endoscopy (IEE), studies have demonstrated IEE has high accuracy for diagnosis of GIM. The endoscopic grading system (EGGIM), a new endoscopic risk scoring system for GC, have been shown to accurately identify a wide range of patients with GIM. However, The high diagnostic accuracy of GIM using IEE and EGGIM assessments performed all require much experience, which limits the application of EGGIM. The investigators aim to design a computer-aided diagnosis program using deep neural network to automatically evaluate the extent of IM and calculate the EGGIM scores.
99 studies on the registry are indexed under Metaplasia; 12 are open to participants now.
This study's planned enrollment of 600 is above the median of 253 across 48 observational studies indexed under Metaplasia.
Browse Metaplasia studies →Shandong University is the lead sponsor of 284 studies on the registry; 59 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Consecutive patients who receive the IEE examination and screened that fulfill the eligibility criteria at Qilu Hospital, Shandong University will be enrolled into the study
Exclusion Criteria:
This group of images is used for training the algorithm of the artificial intelligence
This group of images is used for testing the algorithm of the artificial intelligence
The specificity of AI model to assess the degree of intestinal metaplasia in an endoscopic picture
The specificity of AI model to assess the degree of intestinal metaplasia in an endoscopic picture
Time frame: 2 years
The accuracy of AI model to assess the degree of intestinal metaplasia in an endoscopic picture
The accuracy of AI model to assess the degree of intestinal metaplasia in an endoscopic picture
Time frame: 2 years
The sensitivity of AI model to assess the degree of intestinal metaplasia in an endoscopic picture
The sensitivity of AI model to assess the degree of intestinal metaplasia in an
Time frame: 2 years
Accuracy of the experienced endoscopists to assess the degree of intestinal metaplasia
Accuracy of the experienced endoscopists to assess the degree of intestinal metaplasia in an endoscopic picture
Time frame: 2 years
Accuracy of the inexperienced endoscopists to assess the degree of intestinal metaplasia
Accuracy of the inexperienced endoscopists to assess the degree of intestinal metaplasia in an endoscopic picture
Time frame: 2 years
Inter-observer agreement among experienced endoscopists in identifying the degree of intestinal metaplasia
Inter-observer agreement among experienced endoscopists in identifying the degree of intestinal metaplasia in an endoscopic picture
Time frame: 2 years
Inter-observer agreement among inexperienced endoscopists in identifying degree of intestinal metaplasia
Inter-observer agreement among inexperienced endoscopists in identifying degree of intestinal metaplasia in an endoscopic picture
Time frame: 2 years
Plan to share: No
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This study is status unknown, as verified in Jul 2022. You cannot join it, but the record below documents what was studied.
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Shandong University