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CompletedNCT05440305Updated Jun 30, 2022

Unicentric Form of Castleman Disease - Surgery Therapy Benefit

An observational study in Castleman Disease, Unicentric Castleman Disease and Surgery, sponsored by Charles University, Czech Republic. Completed. Per ClinicalTrials.gov, last updated 2022-06-30.

Sponsored by Charles University, Czech Republic · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
20
Sex
All
01

Study summary

Observation study on patients with unicentric form of Castleman disease, evaluation of surgical treatment benefit. Observation of surgical treatment strategy.

02

Conditions studied

  • Castleman Disease
  • Unicentric Castleman Disease
  • Surgery

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Keywords

  • Unicentric form of Castleman disease
  • Surgical resection
03

In context

Castleman Disease

33 studies on the registry are indexed under Castleman Disease; 10 are open to participants now.

This study's enrollment of 20 is below the median of 265 across 10 observational studies indexed under Castleman Disease.

Browse Castleman Disease studies →

Lead sponsor

Charles University, Czech Republic is the lead sponsor of 220 studies on the registry; 76 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Group of patients with unicentric form of Castleman disease

Inclusion criteria

  • patient with unicentric form of Castleman disease
  • underwent surgery resection

Exclusion criteria

Exclusion Criteria:

  • multilocalised Castleman disease
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
20 participants (actual)
Patient registry
No

Interventions

  • Proceduresurgery type/exstirpation/debulking

    Evaluation of benefit according to surgery

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What researchers measure

Primary outcomes

  1. 5 year survival

    surgery treatment success

    Time frame: each 6 months checkup, up to 150 weeks, from date of randomization until the date of first documented progression

  2. recurence rate

    surgery treatment success

    Time frame: each 6 months checkup, up to 150 weeks, from date of randomization until the date of first documented progression

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Study locations

No study locations are listed for this record.

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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 30, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05440305
Lead sponsor
Charles University, Czech Republic
Responsible party
Jiri Molacek (Principal investigator, Charles University, Czech Republic) — Principal investigator
First posted
Jun 30, 2022
Start date
Jan 1, 2011
Primary completion
Dec 31, 2021
Completion
Apr 30, 2022
Last update
Jun 30, 2022

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2022. You cannot join it, but the record below documents what was studied.

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