An interventional study of Meniscus Allograft Transplantation with Proximal Row Carpectomy and Proximal Row Carpectomy in Wrist Osteoarthritis, sponsored by University of Colorado, Denver. Recruiting at 1 site in United States. Open to participants aged 30 Years to 80 Years. Per ClinicalTrials.gov, last updated 2025-02-10.
Sponsored by University of Colorado, Denver · Not applicable, Interventional, and Treatment
This study plans to learn more about the effect of adding tissue graft for wrist osteoarthritis reconstruction procedures. Previous studies have shown better allograft stability, and no documented foreign body reaction than with silicone and other synthetic materials.
University of Colorado, Denver is the lead sponsor of 1,538 studies on the registry; 318 are open to participants now.
Of its 146 completed or terminated interventional studies of FDA-regulated products, 92 (63%) have results posted.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
These patients will receive a tissue allograft with their wrist reconstruction procedure.
Procedure: Meniscus Allograft Transplantation with Proximal Row Carpectomy
These patients will receive the standard proximal row carpectomy procedure.
Procedure: Proximal Row Carpectomy
Supplementing the wrist reconstruction with a meniscal allograft to improve wrist function and pain scores.
Standard proximal row carpectomy with no tissue or synthetic adjuncts
DISABILITIES OF THE ARM, SHOULDER AND HAND Score: Baseline/Pre-op
Participant wrist disability score will be assessed before and after their wrist reconstruction procedure. Disability of the arm, shoulder and hand (DASH) score ranges from (0-100) with higher score being worse and representing more disability. Lower scores are better and represent less disability. The questionnaire contains 11 questions about daily tasks which are rated 1 (no difficulty) to 5 (Unable to perform) for each question.
Time frame: Preoperatively
DISABILITIES OF THE ARM, SHOULDER AND HAND Score: 2 weeks
Participant wrist disability score after their wrist reconstruction procedure. Disability of the arm, shoulder and hand (DASH) score ranges from (0-100) with higher score being worse and representing more disability. Lower scores are better and represent less disability. The questionnaire contains 11 questions about daily tasks which are rated 1 (no difficulty) to 5 (Unable to perform) for each question.
Time frame: 2 weeks
DISABILITIES OF THE ARM, SHOULDER AND HAND Score: 6 weeks
Participant wrist disability score after their wrist reconstruction procedure. Disability of the arm, shoulder and hand (DASH) score ranges from (0-100) with higher score being worse and representing more disability. Lower scores are better and represent less disability. The questionnaire contains 11 questions about daily tasks which are rated 1 (no difficulty) to 5 (Unable to perform) for each question.
Time frame: 6 weeks
DISABILITIES OF THE ARM, SHOULDER AND HAND Score: 3 months
Participant wrist disability score after their wrist reconstruction procedure. Disability of the arm, shoulder and hand (DASH) score ranges from (0-100) with higher score being worse and representing more disability. Lower scores are better and represent less disability. The questionnaire contains 11 questions about daily tasks which are rated 1 (no difficulty) to 5 (Unable to perform) for each question.
Time frame: 3 months
DISABILITIES OF THE ARM, SHOULDER AND HAND Score: 6 months
Participant wrist disability score after their wrist reconstruction procedure. Disability of the arm, shoulder and hand (DASH) score ranges from (0-100) with higher score being worse and representing more disability. Lower scores are better and represent less disability. The questionnaire contains 11 questions about daily tasks which are rated 1 (no difficulty) to 5 (Unable to perform) for each question.
Time frame: 6 months
DISABILITIES OF THE ARM, SHOULDER AND HAND Score: 9 months
Participant wrist disability score after their wrist reconstruction procedure. Disability of the arm, shoulder and hand (DASH) score ranges from (0-100) with higher score being worse and representing more disability. Lower scores are better and represent less disability. The questionnaire contains 11 questions about daily tasks which are rated 1 (no difficulty) to 5 (Unable to perform) for each question.
Time frame: 9 months
DISABILITIES OF THE ARM, SHOULDER AND HAND Score: 12 months
Participant wrist disability score after their wrist reconstruction procedure. Disability of the arm, shoulder and hand (DASH) score ranges from (0-100) with higher score being worse and representing more disability. Lower scores are better and represent less disability. The questionnaire contains 11 questions about daily tasks which are rated 1 (no difficulty) to 5 (Unable to perform) for each question.
Time frame: 12 months
DISABILITIES OF THE ARM, SHOULDER AND HAND Score: 24 months
Participant wrist disability score after their wrist reconstruction procedure. Disability of the arm, shoulder and hand (DASH) score ranges from (0-100) with higher score being worse and representing more disability. Lower scores are better and represent less disability. The questionnaire contains 11 questions about daily tasks which are rated 1 (no difficulty) to 5 (Unable to perform) for each question.
Time frame: 24 months
Pain Score
Visual Analog Pain Score
Time frame: Preoperatively, up to 24 Months
Radiographic joint spacing
Measurement of joint spacing in the wrist in millimeters.
Time frame: 3 months, up to 24 Months
MRI Joint Spacing
Wrist joint spacing measurements in millimeters using Magnetic resonance imaging (MRI)
Time frame: 9 Months, 24 Months
Plan to share: No
No publications or documents are linked to this record.
Started Sep 2023 (actual). Primary completion is estimated for Dec 2026, 39 months after the start.
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