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RecruitingNCT05389956Updated Mar 19, 2024

Identification of Risk Factors for Cardiovascular Disease and Cancer in Korean Population: A Prospective Cohort Study

An observational study in Cardiovascular Diseases, Malignancy and Risk Factor, sponsored by Ulsan University Hospital. Recruiting at 1 site in Korea, Republic of. Open to participants aged 19 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-03-19.

Sponsored by Ulsan University Hospital · Observational

From the registry’s dates

  • Started Jan 2023; still recruiting 3 years 9 months later.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
510,000
Ages
19 Years and older
Sex
All
01

Study summary

Cancer and cardiovascular disease are the global leading causes of death. These two disease entities are multifactorial disease that are caused by several factors. The aim of this prospective cohort study was to investigate the status of risk factors profiles and health related behavior in Korean population, and to discover novel risk factors associated with the occurrence of endpoint events.

Read the detailed description

This is a single center, observational, prospective cohort study. The primary outcomes include the incidence of MACE (major adverse cardiovascular events) and the incidence of any malignancy. We plan to collect the baseline information at enrollment and the occurrence of clinical endpoint events will be followed for at least 10 years. The study will enroll 510,000 subjects aged ≥19 years who underwent a general health screening in Korea.

02

Conditions studied

  • Cardiovascular Diseases
  • Malignancy
  • Risk Factor

Keywords

  • Cardiovascular disease
  • Malignancy
  • Risk factor
03

In context

Neoplasms

9,365 studies on the registry are indexed under Neoplasms; 2,489 are open to participants now.

This study's planned enrollment of 510,000 is above the median of 204 across 1,683 observational studies indexed under Neoplasms.

Browse Neoplasms studies →

Lead sponsor

Ulsan University Hospital is the lead sponsor of 26 studies on the registry; 5 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
19 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

Health screening participants aged 19 years and older from community and workplace

Inclusion criteria

  • Men or women aged 19 years and older who underwent a general health screening at the health promotion center of Ulsan University Hospital (Ulsan, Korea)
  • Subjects have to agree to participate by signing a consent

Exclusion criteria

Exclusion Criteria:

  • Subjects who cannot or reject to sign the consent form.
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
510,000 participants (estimated)
Patient registry
No

Groups and cohorts

  • Ulsan University Hospital-Health Screening Cohort (UUH-HEALS)

    Ulsan University Hospital-Health Screening Cohort is a prospective cohort of participants who participated in general health screening programs at the Health Promotion Center of Ulsan University Hospital (Ulsan, South Korea). This cohort includes health screening participants aged 19 years and older from community and workplace. The purpose of this cohort is to offer relevant and useful data on health risk factors in the field of non-communicable diseases such as cardiovascular disease and malignancy.

06

What researchers measure

Primary outcomes

  1. Major adverse cardiovascular event (MACE)

    A major adverse cardiovascular event (MACE) of cardiovascular death, nonfatal myocardial infarction, and nonfatal stroke

    Time frame: 10 year

  2. Incidence of malignancy

    The occurrence of any malignancy of interest

    Time frame: 10 year

Secondary outcomes

  1. All-cause death

    Time frame: 10 year

  2. Cardiovascular death

    Time frame: 10 year

  3. Myocardial infarction

    Time frame: 10 year

  4. Stroke

    Time frame: 10 year

  5. Cancer related mortality

    Time frame: 10 year

07

Study locations

1 of 1 sites recruiting
  • Ulsan University Hospital
    Ulsan, 44033, Korea, Republic of
    • Sangwoo Park, MD · Contact · warya7@naver.com
    • Sangwoo Park, MD · Principal investigator
    Recruiting
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 19, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05389956
Lead sponsor
Ulsan University Hospital
Responsible party
Sangwoo Park (MD, Ulsan University Hospital) — Principal investigator
First posted
May 25, 2022
Start date
Jan 1, 2023
Primary completion
Aug 2042 (estimated)
Completion
Aug 2052 (estimated)
Last update
Mar 19, 2024

Study contacts

Sangwoo Park, MD
Contact
warya7@naver.com
82-52-250-8669
Sangwoo Park, MD
principal investigator · Ulsan University Hospital

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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